PATHOGENICITY FACTORS OF CORYNEBACTERIUM NON DIPHTHERIAE

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Abstract

Pathogenicity factors of Corynebacterium non diphtheriae - pili, microcapsule, cell wall, pathogenicity enzymes, toxins, that determine the ability of microorganisms to consequentially interact with epithelium of entry gates of the organism, replicate in vivo, overcome cell and humoral mechanisms of protection, are examined in the review. Particular attention in the paper is given to species of non-diphtheria corynebacteria, that are pathogenic for human and able to produce toxins - Corynebacterium ulcerans and Corynebacterium pseudotuberculosis. Mechanisms of expression regulation of PLD-exotoxins, its interaction with immune system cells are described.

About the authors

G. G. Kharseeva

Rostov State Medical University

Author for correspondence.
Email: noemail@neicon.ru
Russian Federation

N. A. Voronina

Rostov State Medical University

Email: noemail@neicon.ru
Russian Federation

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