SPORADIC AND GROUP IMPORTED CASES OF HEPATITIS E IN ST. PETERSBURG

Aim. Carry out retrospective clinical-epidemiological analysis of sporadic and group cases of acute HE morbidity in St. Petersburg (2000 — 2012). Materials and methods. Medical histories of 11 patients with sporadic morbidity (9 males and 2 females, average age 36±18) and 13 patients involved in group HE morbidity were analyzed. Acute hepatitis E diagnosis was established based on common clinical-epidemiological criteria confirmed by results of biochemical study and data of objective examination. Hepatitis E etiological membership was confirmed by detection in patient blood sera of specific marker of infection — anti-HEV G and M classes with laboratory exclusion of hepatitis A, B and C. Results. Study of epidemiological anamnesis of patients showed that 8 of them were migrants from countries with tropical and subtropical climate. 3 patients were residents of St. Petersburg. In the end of December 2011 and in January 2012 a group HE morbidity was registered among those who had arrived to study in St. Petersburg from India (Mumbai) in a group exceeding 200 individuals. Clinical characteristic of acute HE during sporadic and group morbid- ity is given. Conclusion. The presence of sporadic and group HE morbidity in St. Petersburg indi- cates the necessity to register these situation in organization of protection of the territory of Russia from endogenous HE.

acute hepatitis E, hepatitis E virus, morbidity, clinical manifestations