Email this article MOLECULAR AND GENETIC FEATURES OF THE METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS (MRSA) - CAUSATIVE AGENTS OF PURULENT DISEASES AT CANCER PATIENTS
- Authors: Khokhlova O.E.1,2, Peryanova O.V.1,2, Bobrova O.P.3, Sergeeva V.K.3, Modestov A.A.3, Eremeeva O.G.3, Potkina N.K.2, Kapshuk D.N.1, Alabusheva A.V.1, Yamamoto T...4,5
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Affiliations:
- Krasnoyarsk State Medical University
- Russia-Japan Center of Microbiology, Metagenomics and Infectious Diseases
- Krasnoyarsk Regional Clinical Oncology Center
- Russia-Japan Center of Microbiology
- international Medical Education and Research Center
- Issue: Vol 94, No 6 (2017)
- Pages: 15-20
- Section: Articles
- Submitted: 10.04.2019
- Published: 28.12.2017
- URL: https://microbiol.crie.ru/jour/article/view/224
- DOI: https://doi.org/10.36233/0372-9311-2017-6-15-20
- ID: 224
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Abstract
Aim. Study of the molecular and genetic features of the MRSA, causative agents of purulent diseases at cancer patients. Materials and methods. In the work were used - bacteriological method, molecular genetic methods (PCR, M-PCR, sequencing). Results. MRSA share among staphylococcal infections at cancer patients in 2003 - 2007 has made 37,6%, and in 2010 - 2015 has increased up to 51,3%. At a research of molecular and genetic features of the allocated MRS A ] strains, have established, existence of two main clones: ST239/spa3(t037)/SCCmecIIIA and ST8/ . spal(t008)/SCCmecIVc. Representatives of clones differed in resistance level to antibiotics. Conclusion. In cancer patients in Krasnoyarsk, the distribution of two variants of MRSA-ST239Kra$ and ST8Kras, corresponding to the variants common in the Krasnoyarsk region, was revealed. i
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About the authors
O. E. Khokhlova
Krasnoyarsk State Medical University; Russia-Japan Center of Microbiology, Metagenomics and Infectious Diseases
Author for correspondence.
Email: noemail@neicon.ru
Россия
O. V. Peryanova
Krasnoyarsk State Medical University; Russia-Japan Center of Microbiology, Metagenomics and Infectious Diseases
Email: noemail@neicon.ru
Россия
O. P. Bobrova
Krasnoyarsk Regional Clinical Oncology Center
Email: noemail@neicon.ru
Россия
V. K. Sergeeva
Krasnoyarsk Regional Clinical Oncology Center
Email: noemail@neicon.ru
Россия
A. A. Modestov
Krasnoyarsk Regional Clinical Oncology Center
Email: noemail@neicon.ru
Россия
O. G. Eremeeva
Krasnoyarsk Regional Clinical Oncology Center
Email: noemail@neicon.ru
Россия
N. K. Potkina
Russia-Japan Center of Microbiology, Metagenomics and Infectious Diseases
Email: noemail@neicon.ru
Россия
D. N. Kapshuk
Krasnoyarsk State Medical University
Email: noemail@neicon.ru
Россия
A. V. Alabusheva
Krasnoyarsk State Medical University
Email: noemail@neicon.ru
Россия
T. .. Yamamoto
Russia-Japan Center of Microbiology; international Medical Education and Research Center
Email: noemail@neicon.ru
Россия
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