SOLUBLE FORM OF TRIGGER RECEPTOR EXPRESSED ON MYELOID CELLS-1 AS A MARKER OF BURN WOUND MIXED INFECTION


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Abstract

Aim. Detection of early non-bacteriological markers ofburn wound mixed microbial infection. Materials and methods. The level of soluble form of trigger receptor expressed on myeloid cells-1 (sTREM-1) and cytokines in blood sera of 60 burn patients on days 3 - 6 and 10 - 17 after the burn was studied by solid phase enzyme immunoassay. Results. At the early periods ofburn disease the level of sTREM-1 in sera may be a non-bacteriological marker ofburn wound mixed infection: at days 3 - 6 after the injury - higher than 298.8 pg/ml, at days 10 - 17 after the burn - higher than 294.2 pg/ml. Conclusion. Level of sTREM-1 in blood sera of patients with severe thermic injury could be proposed as an additional laboratory marker ofburn wound mixed microbial infection.

About the authors

A. L Burmistrova

Chelyabinsk State University, Russia

Yu. Yu Filippova

Chelyabinsk State University, Russia

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Copyright (c) 2013 Burmistrova A.L., Filippova Y.Y.

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