DETECTION OF ANTIBODIES TO A/H5N1 INFLUENZA VIRUS IN CITIZENS OF RUSSIAN FEDERATION


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Abstract

Aim. To determine levels of antibodies to influenza virus A/H5N1 in serum samples of people living in different regions of Russia in order to assess the risk of infection with avian influenza H5N1. Materials and methods. Two thousand one hundred sixty-eight se- rum samples were tested by hemagglutination inhibition assay for the presence of antibodies to influenza virus A/H5N1. Results. Twenty-six serum samples obtained from residents of Khanty-Mansiysk Autonomous Area and 2 samples from residents of Novosibirsk region were positive for antibodies to serotype A/H5. There were no clinical cases of avain influenza A/H5N1 infection in medical history of studied persons. Conclusion. Since cases of asymp- tomatic carriage of A/H5N1 influenza virus in water birds are described and ability of the virus to survive in water environment for a long time is shown, it seems logical to detect antibodies to influenza virus A/H5 in sera of subjects living in Russian Federation taking into account that influenza virus A/H5N1 is isolated from wild fowl and poultry since 2005.

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СЛУЧАИ ВЫЯВЛЕНИЯ АНТИТЕЛ К ВИРУСУ ГРИППА А/H5N1 У ЖИТЕЛЕЙ РОССИЙСКОЙ ФЕДЕРАЦИИ
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About the authors

G. G Onischenko

Federal Service for Surveillance for Protection of Consumers Rights and Human Welfare, Moscow,Russia

T. N Ilyicheva

State Scientific Center of Virology and Biotechnology «Vector», Koltsovo, Novosibirsk region,Russia

O. G Kurskaya

State Scientific Center of Virology and Biotechnology «Vector», Koltsovo, Novosibirsk region,Russia

K. M Kolodiy

Center of Hygiene and Epidemiology in Khanty-Mansiysk Autonomous Area, Khanty-Mansiysk, Russia

L. M Yasinskaya

Center of Hygiene and Epidemiology in Khanty-Mansiysk Autonomous Area, Khanty-Mansiysk, Russia

A. G Durymanov

State Scientific Center of Virology and Biotechnology «Vector», Koltsovo, Novosibirsk region,Russia

M. B Ignashkina

State Scientific Center of Virology and Biotechnology «Vector», Koltsovo, Novosibirsk region,Russia

A. V Zaikovskaya

State Scientific Center of Virology and Biotechnology «Vector», Koltsovo, Novosibirsk region,Russia

A. M Shestopalov

State Scientific Center of Virology and Biotechnology «Vector», Koltsovo, Novosibirsk region,Russia

I. G Drozdov

State Scientific Center of Virology and Biotechnology «Vector», Koltsovo, Novosibirsk region,Russia

References

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Copyright (c) 2010 Onischenko G.G., Ilyicheva T.N., Kurskaya O.G., Kolodiy K.M., Yasinskaya L.M., Durymanov A.G., Ignashkina M.B., Zaikovskaya A.V., Shestopalov A.M., Drozdov I.G.

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