NOVEL DIAGNOSTIC KIT ON THE BASIS OF STAINED POLYMERIC CARRIERS FOR EPIDEMIOLOGIC SURVEILLANCE IN NATURAL FOCI OF CRIMEAN-CONGO HEMORRHAGIC FEVER

Aim. To study diagnostic value of developed antigenic polymeric diagnostic kit for epidemiologic surveillance in natural foci of Crimean-Congo hemorrhagic fever (CCHF) in South federal district. Materials and methods . Novel antigenic diagnostic kit on the basis of polymeric microspheres for reaction of volume agglomeration was developed. The kit is designed for detection of virus-specific antibodies in human serum and in serum of agricultural animals. Results . Laboratory and field trials of the kit showed its high diagnostic potency, it was included in methodical recommendations «Organization and accomplishment of measures against CrimeanCongo hemorrhagic fever on the territory of its natural foci in Russia». Use of antigenic polymeric kit for epidemiological surveillance allows for more complete and systemic understanding of CCHF epidemic process. Conclusion . At present, the diagnostic kit is successfully used, alongside with ELISA and PCR, on different levels of epidemiologic surveillance for CCHF in Rostov region.

Crimean-Congo hemorrhagic fever, polymeric microspheres, virus-specific antibodies, reaction of volume agglomeration