CHOLERA VIBRIOS LECTINS AS MAIN PATHOGENICITYAND PERSISTENCE FACTORS(BIOTECHNOLOGICAL ASPECTS OF USE)


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Abstract

Literature data and results of our studies of
lectins are analyzed in the review. All the leading
pathogenicity factors of cholera vibrios that
possess enzymatic activity - cholera toxin,
hemolysin, neuraminidase, chitinase have several
lectin domains, that determine not only
their pathogenetic role but also open perspectives
for their use in medical practice. At the
same time the variable receptor profile of cholera
vibrios cells of various biovars and epidemical
significance established with hemagglutination
inhibition reaction by carbohydrates
could be used to develop new principles of testing
and typing of cholera vibrios.

About the authors

N R Telesmanich

Yu M Lomov

N R Telesmanich

Rostov-on-Don Research Institute of PlagueControl, Russia

Rostov-on-Don Research Institute of PlagueControl, Russia

Yu M Lomov

Rostov-on-Don Research Institute of PlagueControl, Russia

Rostov-on-Don Research Institute of PlagueControl, Russia

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Copyright (c) 2012 Telesmanich N.R., Lomov Y.M., Telesmanich N.R., Lomov Y.M.

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