Email this article CHOLERA VIBRIOS LECTINS AS MAIN PATHOGENICITYAND PERSISTENCE FACTORS(BIOTECHNOLOGICAL ASPECTS OF USE)
- Authors: Telesmanich NR1, Lomov Y.M1, Telesmanich NR2, Lomov Y.M2
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Affiliations:
- Rostov-on-Don Research Institute of PlagueControl, Russia
- Issue: Vol 89, No 2 (2012)
- Pages: 93-99
- Section: Articles
- URL: https://microbiol.crie.ru/jour/article/view/13736
- ID: 13736
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Abstract
Literature data and results of our studies of
lectins are analyzed in the review. All the leading
pathogenicity factors of cholera vibrios that
possess enzymatic activity - cholera toxin,
hemolysin, neuraminidase, chitinase have several
lectin domains, that determine not only
their pathogenetic role but also open perspectives
for their use in medical practice. At the
same time the variable receptor profile of cholera
vibrios cells of various biovars and epidemical
significance established with hemagglutination
inhibition reaction by carbohydrates
could be used to develop new principles of testing
and typing of cholera vibrios.
lectins are analyzed in the review. All the leading
pathogenicity factors of cholera vibrios that
possess enzymatic activity - cholera toxin,
hemolysin, neuraminidase, chitinase have several
lectin domains, that determine not only
their pathogenetic role but also open perspectives
for their use in medical practice. At the
same time the variable receptor profile of cholera
vibrios cells of various biovars and epidemical
significance established with hemagglutination
inhibition reaction by carbohydrates
could be used to develop new principles of testing
and typing of cholera vibrios.
Keywords
About the authors
N R Telesmanich
Yu M Lomov
N R Telesmanich
Rostov-on-Don Research Institute of PlagueControl, RussiaRostov-on-Don Research Institute of PlagueControl, Russia
Yu M Lomov
Rostov-on-Don Research Institute of PlagueControl, RussiaRostov-on-Don Research Institute of PlagueControl, Russia
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