Email this article CHOLERA VIBRIOS LECTINS AS MAIN PATHOGENICITYAND PERSISTENCE FACTORS(BIOTECHNOLOGICAL ASPECTS OF USE)
- Authors: Telesmanich NR1, Lomov Y.M1, Telesmanich NR2, Lomov Y.M2
-
Affiliations:
- Rostov-on-Don Research Institute of PlagueControl, Russia
- Issue: Vol 89, No 2 (2012)
- Pages: 93-99
- Section: Articles
- Submitted: 09.06.2023
- Published: 15.06.2012
- URL: https://microbiol.crie.ru/jour/article/view/13736
- ID: 13736
Cite item
Full Text
Abstract
Literature data and results of our studies of
lectins are analyzed in the review. All the leading
pathogenicity factors of cholera vibrios that
possess enzymatic activity - cholera toxin,
hemolysin, neuraminidase, chitinase have several
lectin domains, that determine not only
their pathogenetic role but also open perspectives
for their use in medical practice. At the
same time the variable receptor profile of cholera
vibrios cells of various biovars and epidemical
significance established with hemagglutination
inhibition reaction by carbohydrates
could be used to develop new principles of testing
and typing of cholera vibrios.
lectins are analyzed in the review. All the leading
pathogenicity factors of cholera vibrios that
possess enzymatic activity - cholera toxin,
hemolysin, neuraminidase, chitinase have several
lectin domains, that determine not only
their pathogenetic role but also open perspectives
for their use in medical practice. At the
same time the variable receptor profile of cholera
vibrios cells of various biovars and epidemical
significance established with hemagglutination
inhibition reaction by carbohydrates
could be used to develop new principles of testing
and typing of cholera vibrios.
Keywords
About the authors
N R Telesmanich
Yu M Lomov
N R Telesmanich
Rostov-on-Don Research Institute of PlagueControl, RussiaRostov-on-Don Research Institute of PlagueControl, Russia
Yu M Lomov
Rostov-on-Don Research Institute of PlagueControl, RussiaRostov-on-Don Research Institute of PlagueControl, Russia
References
- Лахтин В.М. Биотехнология лектинов. Биотехнология. 1989, 5 (6): 676-691.
- Ломов Ю.М., Телесманич Н.Р., Колякина А.В. Специфичность лектиновых рецепторов холерных вибрионов. Журн. микробиол. 2007, 6: 68-72.
- Луцик М.Д., Панасюк Е.Н., Луцик А.Д. Лектины. Львов, Высшая школа, 1981.
- Онищенко Г.Г., Ломов Ю.М., Москвитина Э.А. и др. Холера, обусловленная Vibrio cholerae O1 ctx AB- tcpA+. Журн. микробиол. 2007, 1: 23-29.
- Телесманич Н.Р. Механизмы гемолитической активности холерных вибрионов. Автореф. дисс. д-ра. биол. наук. Ростов-на-Дону, 2006.
- Телесманич Н.Р., Ломов Ю.М., Бардых И.Д. Адгезивные и некоторые другие свойства Vibrio cholerae tcp+ ctx-, изолированных из объектов внешней среды на территории Ростовской области в 2002 г. Журн. микробиол. 2004, 6: 3-6.
- Телесманич Н.Р., Ломов Ю.М., Подосинникова Л.С. Механизмы реализации гемолитической активности холерных вибрионов. Журн. микробиол. 2007, 4: 85-92.
- Allam M., Viallet Y. et al. Cholera toxin triggers apoptosis in human lung cell lines. Cancer Res. 1997, 57 (13): 2615-2618.
- Bernardi A., Cheshev P. Interferinge with the suger code: design and synthsis of oligosaccharide mimicus. Chemistry. 2008, 14 (25): 7434-7441.
- Bhuiyan N.F., Nusrin S. et al. Changino genotypes of cholera toxsin (CT) of Vibrio cholerae O139 in Bangladesh and description of three new CT genotypes. FEMS Immunol. Med. Microbiol. 2009, 57 (2): 136-141.
- Hunt D.E., Gevers D., Vahora N.M. Conservation of the chitin utilization pathway in the Vibrionaceae. Appl. Environ. Microbiol. 2008, 74 (1): 44-51.
- Merrell D.S., Butler S.M., Quardi F. et al. Host-induced epidemic spread of the cholera bacterium. Nature. 2002, 417: 642-645.
- Oswaldo C. The neuraminidase gene is present in the non-toxigenic Vibrio cholerae Amazonia strain: a different allele in comparison to the pandemic strains. Mem. Inst. 2005, 100 (6): 663-669.
- Ouchterlony O., Holmgeren J. Cholera and кelated diarrheas. 43 rd Nobel Symposium co-sponsored by WHO. Stocholm, 1978.
- Sasmal D. Nacetyl-D-dlucosamine specific hemagglutinin receptor of Vibrio cholerae O1 in chicken erythrocyte membrance. FEMS Immunol. Med. Microbiol. 2009, 32 (3): 187-189.
Supplementary files
