PROSPECTS AND PROBLEMS OF USING THE EFFECT OF SURFACE-ENHANCED RAMAN SCATTERING IN THE DIAGNOSIS OF VIRAL INFECTIONS

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Abstract

This review presents the latest advances in the use of surface-enhanced Raman scattering (SERS) immunoassay, which can be used to detect viral markers. As in the case of conventional immunoassays, these methods are often based on «sandwich-type» solid phase immunoassay. In recent years the necessary components of the immunochemical methods with SERS detection is SERS-active substrates to create a variety of approaches have been developed. Despite the difficulty of achieving high sensitivity and specificity in the analysis of clinical samples, a number of successful examples with promising results have been demonstrated.

About the authors

O. V. Borisova

Mechnikov Research Institute of Vaccines and Sera

Author for correspondence.
Email: noemail@neicon.ru
Россия

E. B. Fayzuloev

Mechnikov Research Institute of Vaccines and Sera

Email: noemail@neicon.ru
Россия

A. A. Marova

Mechnikov Research Institute of Vaccines and Sera

Email: noemail@neicon.ru
Россия

V. I. Kukushkin

Institute of Solid State Physics

Email: noemail@neicon.ru
Россия

V. V. Zverev

Mechnikov Research Institute of Vaccines and Sera

Email: noemail@neicon.ru
Россия

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Copyright (c) 2017 Borisova O.V., Fayzuloev E.B., Marova A.A., Kukushkin V.I., Zverev V.V.

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