PROSPECTS AND PROBLEMS OF USING THE EFFECT OF SURFACE-ENHANCED RAMAN SCATTERING IN THE DIAGNOSIS OF VIRAL INFECTIONS

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Abstract

This review presents the latest advances in the use of surface-enhanced Raman scattering (SERS) immunoassay, which can be used to detect viral markers. As in the case of conventional immunoassays, these methods are often based on «sandwich-type» solid phase immunoassay. In recent years the necessary components of the immunochemical methods with SERS detection is SERS-active substrates to create a variety of approaches have been developed. Despite the difficulty of achieving high sensitivity and specificity in the analysis of clinical samples, a number of successful examples with promising results have been demonstrated.

About the authors

O. V. Borisova

Mechnikov Research Institute of Vaccines and Sera

Author for correspondence.
Russian Federation

E. B. Fayzuloev

Mechnikov Research Institute of Vaccines and Sera

Russian Federation

A. A. Marova

Mechnikov Research Institute of Vaccines and Sera

Russian Federation

V. I. Kukushkin

Institute of Solid State Physics

Russian Federation

V. V. Zverev

Mechnikov Research Institute of Vaccines and Sera

Russian Federation

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Copyright (c) 2017 Borisova O.V., Fayzuloev E.B., Marova A.A., Kukushkin V.I., Zverev V.V.

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