ENTEROVIRUS 71: EPIDEMIOLOGY AND DIAGNOSTICS


Cite item

Full Text

Abstract

In 1970s enterovirus type 71 (EV71) caused several epidemics of poliomyelitis-like disease with severe neurologic sequelae. In the last 20 years EV71 was the cause of series of outbreaks and epidemics of foot-and-mouth disease-like conditions with neurologic sequelae in countries of South-East Asia. During the last epidemic of EV71 infection, which occurred in China in 2008, more than 60,000 cases was registered, 38 of which were lethal. Some aspects of epidemiology and laboratory diagnostics of disease caused by EV71 are considered in this review.

About the authors

A. N Lukashev

Chumakov Institute of Poliomyelitis and Viral Encephalites, Moscow, Russia

G. A Koroleva

Chumakov Institute of Poliomyelitis and Viral Encephalites, Moscow, Russia

V. A Lashkevich

Chumakov Institute of Poliomyelitis and Viral Encephalites, Moscow, Russia

M. I Mikhailov

Chumakov Institute of Poliomyelitis and Viral Encephalites, Moscow, Russia

References

  1. Бабаев А.А., Джабарова З.Л. Мельникова Л.П., Результаты серологического обследования больных паралитическими явлениями и здоровых лиц на энтеровирус 71. В: Вирусы и вирусные инфекции человека. 1981, М., ИПВЭ РАМН, с. 51.
  2. Королева Г.А., Грачева Л.А.Ворошилова М.К. Выделение энтеровируса типа 71 от больных с полиомиелитоподобным заболеванием во время вспышки в Болгарии. Вопр вирусол. 1978, 611—618.
  3. Лашкевич В.А., Королева Г.А., Лукашев А.Н. Современные доказательства инфекционной этиологии болезней и постулаты Коха. Журн. микробиол. 2002, 6: 117—121.
  4. Лашкевич В.А., Королева Г.А., Лукашев А.Н. и др. Острый энтеровирусный увеит у детей раннего возраста. Вопр вирусол. 2005, 50: 36—45.
  5. Лашкевич В.А., Королева Г.А., Терешкина Н.В. и др. Сверхострый летальный некроз печени у обезьян, инфицированных высокопатогенными вариантами энтеровирусов (вирусы ЕСНО 11 и ЕСНО 19). Там же. 1996, 5: 198—206.
  6. Лукашев А.Н., Резник В.И., Иванова О.Е. и др. Молекулярная эпидемиология вируса ЕСНО 6 — возбудителя вспышки серозного менингита в Хабаровске в 2006 г. Там же. 2008, 53: 16—21.
  7. Методические указания 4.2.2029-05. Санитарновирусологический контроль водных объектов. Роспотребнадзор, 2005.
  8. Методические указания МУ 3.1.1.2163-08. Эпидемиологический надзор и профилактика энтеровирусной (неполио) инфекции. Государственное санитарно-эпидемиологическое нормирование РФ. М., 2008.
  9. Рекомендации по эпидемиологическому надзору за энтеровирусами для поддержки программы ликвидации полиомиелита. Женева, ВОЗ, 2005.
  10. Руководство по лабораторным исследованиям полиомиелита. Женева, ВОЗ, 2005.
  11. Bible J.M., Iturriza-Gomara M., Megson B. et al. Molecular epidemiology of human enterovirus 71 in the United Kingdom from 1998 to 2006. J Clin Microbiol. 2008, 46: 3192—3200.
  12. Bible J.M., Pantelidis P., Chan P.K. et al. Genetic evolution of enterovirus 71: epidemiological and pathological implications. Rev. Med. Virol. 2007, 17: 371—379.
  13. Brown B.A., Oberste S., Alexander J.P. et al. Molecular epidemiology and evolution of enterovirus 71 strains isolated from 1970 to 1998. J. Virol. 1999, 73: 9969—9975.
  14. Chan Y.-F.AbuBakar S. Recombinant human enterovirus 71 in hand, foot and mouth disease patients. Emerg. Infect. Dis. 2004, 10: 1468—1470.
  15. Chang L.Y., Hsia S.H., Wu C.T. et al. Outcome of enterovirus 71 infections with or without stage-based management: 1998 to 2002. Pediatr. Infect. Dis. J. 2004, 23: 327—332.
  16. Chang L.Y., King C.C., Hsu K.H. et al. Risk factors of enterovirus 71 infection and associated hand, foot, and mouth disease/herpangina in children during an epidemic in Taiwan. Pediatrics. 2002, 109: e88.
  17. Chang L.Y., Tsao K.C., Hsia S.H. et al. Transmission and clinical features of enterovirus 71 infections in household contacts in Taiwan. JAMA. 2004, 291: 222—227.
  18. Chen T.C., Chen G.W., Hsiung C.A. et al. Combining multiplex reverse transcription-PCR and a diagnostic microarray to detect and differentiate enterovirus 71 and coxsackievirus A16. J. Clin. Microbiol. 2006, 44: 2212—2219.
  19. Chinese Center for Disease Control and Prevention, Report on the Hand, Foot and Mouth Disease Outbreak in Fuyang City, Anhui Province and the Prevention and Control in China. 2008.
  20. Chu P.Y., Lin K.H., Hwang K.P. et al. Molecular epidemiology of enterovirus 71 in Taiwan. Arch. Virol. 2001, 146: 589—600.
  21. Chumakov M., Voroshilova M., Shindarov L. et al. Enterovirus 71 isolated from cases of epidemic poliomyelitis-like disease in Bulgaria. Ibid. 1979, 60: 329—340.
  22. Gomes M.L., de Castro C.M., Oliveira M.J. et al. Neutralizing antibodies to enterovirus 71 in Belem, Brazil. Mem. Inst. Oswaldo Cruz. 2002, 97: 47—49.
  23. Herrero L.J., Lee C.S., Hurrelbrink R.J. et al. Molecular epidemiology of enterovirus 71 in peninsular Malaysia, 1997—2000. Arch. Virol. 2003, 148: 1369—1385.
  24. Ho M., Chen E.R., Hsu K.H. et al. An epidemic of enterovirus 71 infection in Taiwan. Taiwan Enterovirus Epidemic Working Group. N. Engl. J. Med. 1999, 341: 929—935.
  25. Khetsuriani N., Lamonte-Fowlkes A., Oberste S. et al. Enterovirus surveillance-United States, 1970—2005. MMWR Surveill. Summ. 2006, 55: 1—20.
  26. Kung S.H., Wang S.F., Huang C.W. et al. Genetic and antigenic analyses of enterovirus 71 isolates in Taiwan during 1998—2005. Clin. Microbiol. Infect. 2007, 13: 787—787.
  27. Lu C.Y., Lee C.Y., Kao C.L. et al. Incidence and casefatality rates resulting from the 1998 enterovirus 71 outbreak in Taiwan. J. Med. Virol. 2002, 67: 217—223.
  28. Lukashev A.N., Lashkevich V.A., Ivanova O.E. et al. Recombination in circulating enterovirus B: independent evolution of structural and non-structural genome regions. J. Gen. Virol. 2005, 86: 3281—3290.
  29. Melnick J.L., Schmidt N.J., Mirkovic R.R. et al. Identification of Bulgarian strain 258 of enterovirus Intervirology. 1980, 12: 297—302.
  30. Nagy G., Takatsy S., Kukan E. et al. Virological diagnosis of enterovirus type 71 infections: experiences gained during an epidemic of acute CNS diseases in Hungary in 1978. Arch. Virol. 1982, 71: 217—227.
  31. Oberste M.S., Maher K., Kilpatrick D.R. et al. Typing of human enteroviruses by partial sequencing of VP1. J. Clin. Microbiol. 1999, 37: 1288—1293.
  32. Ooi E.E., Phoon M.C., Ishak B. et al. Seroepidemiology of human enterovirus 71, Singapore. Emerg. Infect. Dis. 2002, 8: 995—997.
  33. Ooi M.H., Solomon T., Podin Y. et al. Evaluation of different clinical sample types in diagnosis of human enterovirus 71-associated hand-foot-and-mouth dis- ease. J. Clin. Microbiol. 2007, 45: 1858—1866.
  34. Ooi M.H., Wong S.C., Podin Y. et al. Human enterovirus 71 disease in Sarawak, Malaysia: a prospective clinical, virological, and molecular epidemiological study. Clin. Infect. Dis. 2007, 44: 646—656.
  35. Pallansch M.A., Roos R.P. Enteroviruses: polioviruses, coxsackieviruses, echoviruses, and newer enteroviruses. In: Fields virology. D.M. Knipe, P.M. Howley (ed.). Philadelphia. Lippincott-Raven, 2001, p. 724—743.
  36. Schmidt N.J., Lennette E.H., Ho H.H. An apparently new enterovirus isolated from patients with disease of the central nervous system. J. Infect. Dis. 1974, 129: 304—309.
  37. Shindarov L., Chumakov M.P., Voroshilova M. et al. Epidemiological, clinical, and pathological characteristics of epidemic poliomyelitis-like disease caused by enterovirus 71. J. Hyg. Epidemiol. Microbiol. Immunol. 1979, 23: 284—295.
  38. Singh S., Chow V.T., Phoon M.C. et al. Direct detection of enterovirus 71 (EV71) in clinical specimens from a hand, foot, and mouth disease outbreak in Singapore by reverse transcription-PCR with universal enterovirus and EV71-specific primers. J. Clin. Microbiol. 2002, 40: 2823—2827.
  39. Suvilehto J., Roivainen M., Seppänen M. et al. Rhinovirus/enterovirus RNA in tonsillar tissue of children with tonsillar disease. J. Clin. Virol. 2006, 35: 292—297.
  40. Tan E.L., Chow V.T., Kumarasinghe G. et al. Specific detection of enterovirus 71 directly from clinical specimens using real-time RT-PCR hybridization probe assay. Mol. Cell. Probes. 2006, 20: 135—140.
  41. Tan E.L., Tak Kwong Chow V., Quak S.H. et al. Development of multiplex real-time hybridization probe reverse transcriptase polymerase chain reaction for specific detection and differentiation of enterovirus and coxsackievirus A16. Diagn. Microbiol. Infect. Dis. 2008, 61: 294—301.
  42. Welch J., Maclaran K., Jordan T. et al. Frequency viral loads, and serotype identification of enterovirus infections in Scottish blood donors. Transfusion. 2003, 43: 1060—1066.
  43. Witso E., Palacios G., Ronningen K.S. et al. Asymptomatic circulation of HEV71 in Norway. Virus Res. 2007, 123: 19—29.
  44. Yan J.J., Wang J.R., Liu C.C. et al. An outbreak of enterovirus 71 infection in Taiwan 1998: a comprehensive pathological, virological, and molecular study on a case of fulminant encephalitis. J. Clin. Virol. 2000, 17: 13—22.

Supplementary files

Supplementary Files
Action
1. JATS XML
Download

Copyright (c) 2009 Lukashev A.N., Koroleva G.A., Lashkevich V.A., Mikhailov M.I.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: ПИ № ФС77-75442 от 01.04.2019 г.


This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies