DETECTION RATE OF MARKERS OF MONOAND MIXED HEMOTRANSMISSIVE VIRAL INFECTIONS IN PATIENTS OF EMERGENCY CARE HOSPITAL


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Abstract

Aim. The objective of this study was to assess dynamics of prevalence of hemotransmissive viral infections (HTVI) markers as monoor mixed infections in patients admitted to Sklifosovsky Research Institute of Emergency Medicine. Materials and methods. Two hundred thirty-five thousands and seventy patients admitted to the Institute during 1998 — 2007 were screened for the presence of laboratory markers of HTVI (antibodies to HIV, HBsAg, and anti-HCV). Results The long-term screening revealed 27,942 (11.9%) persons positive for laboratory markers, of which 3,099 (11.1%) were positive for >1 marker. It was established that HIV infection as well as viral hepatitis B and C have different level of similarity and ability to coexist. HIV infection was more frequently detected in association with other infections, whereas hepatitis B and C — as monoinfections. Conclusion. Attempt to consider the mutual influence of HTVI on their prevalence from the view of modern concept of microorganisms’ ecology was made. Computation of Jaccard similarity coefficient showed that HIV and HCV have the greatest abilities for coexistence, whereas HIV and HBV — the smallest.

About the authors

M. A Godkov

Sklifosovsky Research Institute of Emergency Medicine; Sechenov Moscow Medical Academy, Moscow, Russia

N. I Briko

Sklifosovsky Research Institute of Emergency Medicine; Sechenov Moscow Medical Academy, Moscow, Russia

References

  1. Асратян А.А., Каражас Н.В., Казарян С.М. и др. Инфицированность вирусами гепатитов В и С больных с оппортунистическими инфекциями. Эпидемиол. инфекц. бол. 2003, 3: 28 — 30.
  2. Гавура В.В. Вирусный гепатит и СПИД. Клин. мед. 1993, 6: 15 — 19.
  3. Годков М.А. Частота выявления и распределения ВИЧ-инфицированных пациентов в многопрофильном стационаре скорой медицинской помощи. Журн. микробиол. 2004, 1: 38 — 41.
  4. Годков М.А Микствирусные инфекции у пациентов стационара скорой медицинской помощи. Эпидемиол. инфекц. бол. 2007, 5: 28 — 30.
  5. Ермолов А.С., Годков М.А. Частота выявления пациентов с различными сочетаниями гемоконтактных вирусных инфекций (ВИЧинфекция, гепатиты В и С) в стационаре скорой помощи. В: Внутрибольничные инфекции в стационарах различного профиля, профилактика, лечение осложнений. М., 2006, с. 17 — 19.
  6. Сюткин В.Е.Сочетанная инфекция гепатотропными вирусами. Росс. мед. журн. 2004, 2: 52 — 57.
  7. Guitton E., Montastruct J.L., Lapeyre-Mestre M. Influence of HCV or HBV infection on adverse drug reaction to antiretroviral drugs in HIV patients. Eur. J. Clin. Pharmacol. 2006, 17: 1 — 7.
  8. Wittakker R.H. Сообщества и экосистемы. М., Прогресс, 1980.

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Copyright (c) 2009 Godkov M.A., Briko N.I.

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