Email this article IMMUNITY TO POLIOVIRUSES IN CHILDREN POPULATION OF VARIOUS TERRITORIES OF THE RUSSIAN FEDERATION
- Authors: Romanenkova NI1, Bichurina MA1, Rozaeva NR1, Shishko LA1
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Affiliations:
- Issue: Vol 89, No 5 (2012)
- Pages: 49-53
- Section: Articles
- URL: https://microbiol.crie.ru/jour/article/view/14193
- ID: 14193
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Abstract
Aim. Analyze the state of population immunity to polioviruses in children population of 14 administrative
territories of the Russian Federation. Materials and methods. Antibody titers against reference vaccine poliovirus
serotypes 1, 2 and 3 were determined by using neutralization reaction in cell culture Hep-2. Results.
Several years after the termination of conduction of National immunizations days the percent of seronegative
children was shown to increase, especially to poliovirus serotype 3, in most of the territories. Possible reasons
for fluctuation of geometric mean antibody titers against polioviruses in children in various territories as well
as in various years in the same territory were established. Conclusion. Quality vaccine prophylaxis and control
of population immunity state among children population play an important role in the maintenance of Russian
Federation status as a country is free from poliomyelitis.
territories of the Russian Federation. Materials and methods. Antibody titers against reference vaccine poliovirus
serotypes 1, 2 and 3 were determined by using neutralization reaction in cell culture Hep-2. Results.
Several years after the termination of conduction of National immunizations days the percent of seronegative
children was shown to increase, especially to poliovirus serotype 3, in most of the territories. Possible reasons
for fluctuation of geometric mean antibody titers against polioviruses in children in various territories as well
as in various years in the same territory were established. Conclusion. Quality vaccine prophylaxis and control
of population immunity state among children population play an important role in the maintenance of Russian
Federation status as a country is free from poliomyelitis.
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References
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