STUDY OF PREVALENCE OF RARE AND DIFFICULT TO CULTIVATE CAUSATIVE AGENTS OF INFLAMMATORY DISEASES OF RESPIRATORY ORGANS

Aim. Study the prevalence of Mycoplasma pneumoniae, Chlamydophila pneumoniae, Chlamydophila psittaci,
Legionella pneumophila, Moraxella catarrhаlis, Cytomegalovirus, Herpes simplex I/II virus (HSV I/II)
in individuals of various age groups with varying inflammatory broncho-pulmonary diseases. Materials and
methods. 384 adults and 1001 children with clinically confirmed diagnoses were examined by PCR method:
community-acquired pneumonia, acute bronchitis, bronchial asthma, ARD/ARVD, as well as 127 healthy
children and 52 healthy adults. Sputum, smears from posterior fornix of pharynx, blood, saliva from children
of the first year of life were used as material for the study. Results. Wide prevalence of M. pneumoniaе and C.
pneumoniaе among adults and M. pneumoniaе among children older than 1 year with inflammatory diseases
of respiratory organs was established. C. psittaci, L. pneumophila, M. catarrhаlis occurred in isolated
cases in both adults and children. Active replication of herpes group viruses was detected in patients of all age
groups with inflammatory broncho-pulmonary diseases, and in children Cytomegalovirus replication predominated,
in adults - HSV I/II. Conclusion. High frequency of prevalence of M. pneumoniaе and C.
pneumoniaе in inflammatory diseases of respiratory tract was established, giving evidence of reasonability and
necessity of examination of patients with various nosologic forms of diseases for these species of microorganisms
with the aim of effective etiotropic therapy.

Mycoplasma pneumoniae, Chlamydophila pneumoniae, Chlamydophila psittaci, Legionella pneumophila, Cytomegalovirus, pneumoniae, Chlamydophila pneumoniae, C.psittaci, Legionella pneumophila, Cytomegalovirus, Herpes simplex I/II virus, inflammatory diseases of respiratory organs