SPECIES AND QUANTITATIVE CHARACTERISTICS OF PHARYNGEAL MUCOSA MICROFLORA IN PREGNANT WOMEN

Aim. Species and quantitative characteristics of upper respiratory tract (URT) mucosa microflora in women at gestation period. Materials and methods. The results of a bacteriological study of 68 samples of mucus from posterior pharyngeal wall in women at gestation period (from 14 weeks), 52 of those - from pregnant women with acute respiratory infection (ARI) symptoms and 16 - from women without signs of disease, are presented. Qualitative and quantitative composition of microflora was studied by a generally accepted bacteriological method. Results. During primary bacteriological study 111 microorganism cultures were isolated. 88 (79.3%) of strains belonged to Gram-positive flora, 20 (18.0%) - to Gram-negative, and Candida genus fungi constituted 3 (2.7%) isolates. Streptococcus pyogenes and Moraxella catarrhalis were isolated from pregnant women with ARI signs at 23.1% and 5.8% frequency of occurrence, respectively. A higher detectability of Staphylococcus aureus - in 31.3% and Candida spp. - in 6.3% of women who did not complain as opposed to patients with URT lesions (in 21.2 and 3.9%, respectively) was determined. In patients without ARI signs the amount of bacteria did not exceed 10 5 - 10 6 CFU/ml, in pregnant women with ARI diagnosis in 8 of 52 cases semination of pharyngeal mucus was observed - 10 7 - 10 8 CFU/ml. Conclusion. Prevalence of S. aureus, Streptococcus agalactiae, S. pyogenes, Streptococcus mutans in composition of pharyngeal mucus microflora ofpregnant women both with URT lesion signs and without them was shown, however the degree of semination by pathogens in the groups was different that determined the severity of disease manifestations.

upper respiratory tract mucosa, pregnant women, microflora