Email this article COMPLEX EVALUATION OF INTESTINE MICROBIOCENOSIS CONDITION IN PATIENTS WITH CHRONIC PANCREATITIS
- Authors: Gorovits E.S1, Tokareva E.V1, Khlynova O.V1, Zhelobov V.G1, Elkin V.D1
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Affiliations:
- Perm State Medical Academy, Russia
- Issue: Vol 90, No 4 (2013)
- Pages: 73-76
- Section: Articles
- Submitted: 09.06.2023
- Published: 15.08.2013
- URL: https://microbiol.crie.ru/jour/article/view/13865
- ID: 13865
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Abstract
Aim. Study the state of intestine microbiocenosis in patients with chronic pancreatitis, give comparative evaluation of diagnostic significance of bacterial and gas-liquid chromatography analysis. Materials and methods. 96 patients with chronic pancreatitis (CP) were examined bacteriologically for dysbacteriosis. In parallel in 42 individuals gas-liquid chromatography analysis (GLC-analysis) was carried out. Results. During bacteriological examination in 93.7% of patients various dysbiotic disorders were detected. The main indicators of GLC-analysis - anaerobic index, cumulative content of volatile fatty acids and their isoforms also gave evidence on imbalance of intestine microflora. GLC-analysis as a rule confirmed the data of bacteriological examination. Conclusion. During parallel use ofbacteriological and gas-liquid chromatography analysis in almost all the CP patients intestine dysbacteriosis of various degree of intensity was detected. Combined use of these methods increases effectiveness of examination.
About the authors
E. S Gorovits
Perm State Medical Academy, Russia
E. V Tokareva
Perm State Medical Academy, Russia
O. V Khlynova
Perm State Medical Academy, Russia
V. G Zhelobov
Perm State Medical Academy, Russia
V. D Elkin
Perm State Medical Academy, Russia
References
- Алешукина А.В. Комплексный способ диагностики степени выраженности дисбактериоза кишечника. Клиническая лабораторная диагностика. 2010, 11: 48-51.
- Ардатская М.Д., Минушкин О.Н., Иконников Н.С. Дисбактериоз кишечника: понятие, диагностические подходы и пути коррекции. Возможности и преимущества биохимического исследования кала. Пособие для врачей. М., 2004.
- Ардатская М.Д., Минушкин О.Н., Прихно Н.И и др. Летучие жирные кислоты и их диагностическое и прогностическое значение в гастроэнтерологической практике. Рос. журн. гастроэнетрол. гепатол. колопроктол. 2000, 5: 63-70.
- Бондаренко В.М., Воробьев А.А. Дисбиозы и препараты с пробиотической функцией. Журн. микробиол. 2004, 1: 84-92.
- Минушкин О.Н. Дисбактериоз кишечника: современное состояние проблемы. Consilium medicum. 2007, 9 (7): 58-61.
- Отраслевой Стандарт «Протокол ведения больных. Дисбактериоз кишечника». ОСТ 91500.11.0004-2003.
- Schneider A., Lohr J. M., Singer M. V. The M-ANNHEIN - classification of chronic pancreatitis: Introduction of a unifying classification system based on review of previous classification of the disease. J. Gastroenterology. 2007, 42: 10-119.
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