Email this article THE ROLE OF EPIDEMIOLOGIC SURVEILLANCE OF MIGRANTS IN THE SYSTEM OF POLIOMYELITISCONTROL
- Authors: Romanenkova NI1, Bichurina MA1, Rozaeva NR1, Pogrebnaya TN1, Romanenkova NI2, Bichurina MA2, Rozaeva NR2, Pogrebnaya TN3
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Affiliations:
- Pasteur Research Institute of Epidemiology and Microbiology, St. Petersburg
- Centre of Hygiene and Epidemiologyin Kaliningrad region, Kaliningrad, Russia
- Issue: Vol 89, No 6 (2012)
- Pages: 27-31
- Section: Articles
- Submitted: 09.06.2023
- Published: 15.12.2012
- URL: https://microbiol.crie.ru/jour/article/view/13704
- ID: 13704
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Abstract
of immunity against polioviruses in these children. Materials and methods. 1668 feces samples from patients
with acute flaccid paralysis and contact individuals and 479 feces samples from healthy children from families
of migrants, as well as 1012 blood sera of children aged 3 - 4 and 14 - 15 years living in the same territory
of Russia, and 169 blood sera of children of migrants were studied. Polioviruses and non-polio enteroviruses
were isolated by standard procedures recommended by WHO in 3 cell cultures - RD, L20B and
Hep-2. Virus identification was carried out by microneutralization test with rabbit antisera against poliomyelitis
virus, RIVM (Bilthoven, Netherlands). For intra-type differentiation EIA and PCR were used. Antibody
titers were determined in microneutralization reaction with reference poliovirus vaccines strains in Hep-2
cell culture. Results. The frequency of detection of polioviruses in children of migrants was significantly
higher than in patients with acute flaccid paralysis. In a larger percent of cases children of migrants did not
have protective antibody titers against polioviruses of all the 3 serotypes. Conclusion. Migrants as a significant
source of poliovirus detection may be an indicator group for detection of signs of unfavorable epidemic situation.
Based on the results of epidemiologic surveillance of migrants the fact of import of wild poliovirus
into North-West of Russia with the absence of poliomyelitis was proven, which confirms an important role
of this form of monitoring in the system of poliomyelitis control.
Keywords
About the authors
N I Romanenkova
M A Bichurina
N R Rozaeva
T N Pogrebnaya
N I Romanenkova
Pasteur Research Institute of Epidemiology and Microbiology, St. PetersburgPasteur Research Institute of Epidemiology and Microbiology, St. Petersburg
M A Bichurina
Pasteur Research Institute of Epidemiology and Microbiology, St. PetersburgPasteur Research Institute of Epidemiology and Microbiology, St. Petersburg
N R Rozaeva
Pasteur Research Institute of Epidemiology and Microbiology, St. PetersburgPasteur Research Institute of Epidemiology and Microbiology, St. Petersburg
T N Pogrebnaya
Centre of Hygiene and Epidemiologyin Kaliningrad region, Kaliningrad, RussiaCentre of Hygiene and Epidemiologyin Kaliningrad region, Kaliningrad, Russia
References
- Бичурина М.А., Лялина Л.В., Романенкова Н.И., Розаева Н.Р. Итоги сертификации ликвидации полиомиелита на территориях СЗФО. СПб, 2003.
- Бичурина М.А., Романенкова Н.И., Розаева Н.Р. и др. Глобальная ситуация по полиомиелиту. Стратегия и тактика ВОЗ по ликвидации полиомиелита. Журн. инфектол. 2011, 2: 5-14.
- Иванова О.Е., Романенкова Н.И., Еремеева Т.П. и др. Риск развития случаев острого вялого паралича и вакциноассоциированного полиомиелита в закрытых детских коллективах - домах ребенка и детских лечебных стационарах. Эпидемиол. вакцинопроф. 2005, 1: 14-18.
- Онищенко Г.Г., Дроздов С.Г., Лялина Л.В. и др. Проблемы ликвидации полиомиелита. СПб, 2008.
- Романенкова Н.И., Бичурина М.А., Розаева Н.Р. Характеристика вакцинных полиовирусов, выделенных в закрытых детских кол- лективах (домах ребенка). Вопр. вирусол. 2010, 2: 42-45.
- Романенкова Н.И., Бичурина М.А., Розаева Н.Р., Шишко Л.А. Изучение иммунитета к полиовирусам на отдельных молчащих территориях Российской Федерации. Инфекция и иммунитет. 2011, 2: 161-166.
- Cherkasova E.A., Yakovenko M.L., Rezapkin G.V. et al. Spread of vaccine-derived poliovirus from a paralytic case in an immunodeficient child: an insight into the natural evolution of oral polio vaccine. J. Virol. 2005, 79: 1062-1070.
- Polio weekly global update (WHO). 19 January 2011.
- Polio weekly global update (WHO). 16 November 2011
- Polio weekly global update (WHO). 29 February 2012.
- Polio laboratory manual. WHO/IVB/04.10. World Health Organization, Geneva, 2004.
- Romanenkova N.I., Guillot S., Rozaeva N.R. et al. Use of a multiple restriction fragment length polymorphism method for detecting vaccinederived polioviruses in clinical samples. J. Clin. Microbiol. 2006, 44, 11: 4077-4084.
- Van der Avoort H.G., Hull B.P., Hovi T. et al. Comparative study of five methods for intratypic differentiation of polioviruses. J. Clin. Microbiol. 1995, 33: 2562-2566.
- Yakovenko M., Ivanova O., Gmyl A. et al. Poliomyelitis outbreak in Tajikistan in 2010 caused by wild poliovirus type 1. Europic 2010, Scotland, G2: 125.
- Yang C.F., De L., Holloway B.P. et al. Detection and identification of vaccine-related polioviruses by the polymerase chain reaction. Virus Res. 1991, 20: 159-179.
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