PERSPECTIVES OF CREATION OF VACCINES AGAINST TICK BITE FOR NONSPECIFIC PROPHYLAXIS OF VECTOR BORNE DISEASES


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Abstract

Prophylaxis of infectious diseases transferred by ticks is an important problem of contemporary medicine. One of the perspective approaches to solve this problem is the creation of vaccines against tick bite (anti-tick vaccines). Contemporary methods of the control of infectious diseases transferred by ticks are described in the review. Features of naturally and artificially acquired immunity against ticks are examined. Candidate tick antigens for the construction of vaccines against genus Ixodes tick bite are described. Perspectives of use of anti-tick vaccines against tick vector borne diseases are evaluated.

About the authors

I. A Dyatlov

State Scientific Center of Applied Microbiology and Biotechnology, Obolensk, Moscow region, Russia

S. F Biketov

State Scientific Center of Applied Microbiology and Biotechnology, Obolensk, Moscow region, Russia

V. V Firstova

State Scientific Center of Applied Microbiology and Biotechnology, Obolensk, Moscow region, Russia

References

  1. Коренберг Э.И. Изучение и профилактика микстинфекций, передающихся иксодовыми клещами. Вестн. РАМН. 2001, 11: 41-45.
  2. Малеев В.В. Рекомендации по диагностике клещевых боррелиозов. Клин. микробиол. антимикроб. химиотер. 2005, 7 (2): 130-153.
  3. Павловский Е.Н. Клещи и клещевой энцефалит. В: Паразитология Дальнего Востока. Л., 1947, с. 212-264.
  4. Allen J.R. Tick resistance: basophils in skin reactions of resistant guinea pigs. Int. J. Parasitol. 1973, 3:195-200.
  5. Almazan C., Blas-Machado U., Kocan K.M. et al. Characterization of three Ixodes scapularis cDNAs protective against tick infestations. Vaccine. 2005, 23: 4403-1416.
  6. Almazan C., Kocan K.M., Bergman D.K. et al. Identification of protective antigens for the control of Ixodes scapularis infestations using cDNA expression library immunization. Ibid. 2003, 21: 1492-1501.
  7. Almazan C., Kocan K.M., Blouin E.F., de la Fuente J. Vaccination with recombinant tick antigens for the control of Ixodes scapularis adult infestations. Ibid. 2005, 16; 23 (46-47): 5294-5298.
  8. Anguitta J., Ramamoorthi N., Hovius J.W. et al. Salpl5, an ixodes scapularis salivary protein, inhibits CD4(+) T cell activation. Immunity. 2002, 16: 849-859.
  9. Bechara G.H, Szabo M.P.J., Mukai L.S., Rosa P.C.S. Immunisation of dogs, hamsters and guinea pigs against R. sanguineus using crude unfed adult tick extracts. Vet. Parasitol. 1994, 52: 79-90.
  10. Bell J.F., Stewart J., Wikel S.K. Resistance to tickborne Francisella tularensis by tick-sensitized rabbits: Allergic kendusity. Am. J. Trop. Med. Hyg. 1979, 28: 876.
  11. Brown S.J., Galli S.J., Gleich G.L., Askenase P.W. Ablation of immunity to Amblyomma americanum by antibasophil serum: cooperation between basophils and eosinophils in expression of immunity to ectoparasites (ticks) in guinea pigs. J. Immunol. 1982, 129: 790-796.
  12. Burke G.S, Wikel S.K., Spielman A. Hypersensitivity to Ticks and Lyme Disease. Risk. Emerg. Infect. Dis. 2005, 11 (1): 36-41.
  13. Das S., Gautam В., Deponte K. et al. Salp25D, an Ixodes scapularis antioxidant, is 1 of 14 immunodominant antigens in engorged tick salivary glands. J. Infect. Dis. 2001, 184 (8): 1056-1064.
  14. Das S., Marcantonio N., Deponte K. et al. SALP16, Agene induced in Ixodes scapularis salivary glands during tick feeding. Am. J. Trop. Med. Hyg. 2000, 62 (1): 99-105.
  15. de Vos S., Zeinstra L., Taoufik O. et al. Evidence for the utility of the Bm86 antigen from Boophilus microplus in vaccination against other tick species. Exp. Appl. Acarol. 2001, 25: 245-261.
  16. Elvin С.М., Kemp D.H. Generic approaches to obtaining efficacious antigens from vector arthropods. Int. J. Parasitol. 1994, 24: 67-79.
  17. Fivaz B.H., Norval R.A.I. Observations on successive infestations of the rabbit host by the ticks Rhipicephalus appendiculatus and R. zambeziensis (Ixodidae). Exp. Appl. Acarol. 1989, 7: 267-79.
  18. Francis J., Little D.A. Resistance of Droughtmaster cattle to tick infestation and babesiosis. Aust. Vet. J. 1964, 40: 247.
  19. Franz J.K., Krause A. Lyme disease (Lyme borreliosis). Best Pract. Res. Clin. Rheumatol. 2003, 17 (2): 241-264.
  20. Galun R. Research into alternative arthropod control measures against livestock pests. Workshop on ecology and control of external parasites of economic importance on bovines in Latin America. CIAT, Colombia. 1978, p. 155-161.
  21. Hewetson R.W. The inheritance of resistance by cattle to cattle tick. Aust. Vet. J. 1972, 48: 299-303.
  22. Hollander D.N., Allen J.R. Dermacentor variabilis: acquired resistance to ticks in Balb/c mice. Exp. Parasitol. 1985, 59: 118-129.
  23. Imamura S., da Silva Vaz Junior I., Sugino M. et al. A serine protease inhibitor from Haemaphysalis longicornis as an anti-tick vaccine. Vaccine. 2005, 26; 23 (10): 1301-13l1.
  24. Johnston L.A.Y., Kemp D.H., Pearson R.D. Imnunisation of cattle against Boophilus microplus using extracts derived from adult female ticks: effects of induced immunity on tick populations. Int. J. Parasitol. 1986, 16: 27-34.
  25. Jones L.D., Nuttall P.A. The effect of host resistance to tick infestation on the transmission of Thogotovirus by ticks. J. Gen. Virol. 1990, 71: 1039.
  26. Labuda M., Trimnell A.R., Lickova M. et al. An antivector vaccine protects against a lethal vectorborne pathogen. Cv. Antivector Vac. Protect. 2006, 2 (4): 20.
  27. Mattioli R.C., Pandey V.S., Murray M., Fitzpatric J.L. Immunogenic influences on tick resistance in African cattle with particular reference to trypanotolerant N'Dama (Bos taurus) and trypanosusceptible Gobra zebu cattle. Acta Trop. 2000, 75: 263-277.
  28. Nithiuthai S., Allen J.R. Langerhans cells present tick antigens to lymph node cells from ticksensitised guinea pigs. Immunology. 1985, 55: 157-163.
  29. Roberts J.A., Kerr J.D. Boophilus rnicroplus; passive transfer of resistance in cattle. J. Parasitol. 1976, 62: 485-489.
  30. Trager W. Acquired immunity to ticks. Ibid. 1939, 25: 57-78.
  31. Trimnell A.R., Davies G.M., Lissina O. et al. A cross-reactive tick cement antigen is a candidate broad-spectrum tick vaccine. Vaccine. 2005, 23: 4329-4341.
  32. Trimnell A.R., Hails R.S., Nuttall P.A. Dual action ectoparasite vaccine targeting «exposed» and «concealed» antigens. Ibid. 2002, 20: 3560-3568.
  33. Tsuda A., Mulenga A., Sugimoto C. et al. cDNA cloning, characterisation and vaccine effect analysisof Haemaphysalis longicornis tick saliva proteins. Ibid. 2001, 19: 4287-4296.
  34. Valenzuela J.G., Francischetti I.M.B., Pham V.M. Exploring the sialome of the tick Ixodes scapularis. J. Exp. Biol. 2002, 205: 2843-2864.
  35. Walker A.R., Fletcher J.D. Histological study of the attachment sites of adult Rhipicephalus appendiculatus ticks on rabbits and cattle. Int. J. Parasitol. 1986, 16: 399-413.
  36. Wikel S.K. Host immunity to ticks. Annu. Rev. Entomol. 1996, 41: 1-22.
  37. Wikel S.K., Allen J.R. Acquired resistance to ticks. I. Passive transfer of resistance. Immunology. 1976, 30:311-316.
  38. Wikel S.K., Ramachandra R.N., Bergman D.K. et al. Infestation with pathogen-free nymphs of the tick Ixodes scapularis induces host resistance to transmission oiBorrelia burgdorferi by ticks. Infect. Immun. 1997, 65: 335.

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Copyright (c) 2011 Dyatlov I.A., Biketov S.F., Firstova V.V.

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