GENETIC VIRULENCE MARKERS OF OPPORTUNISTIC BACTERIA


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Abstract

The analysis of opportunistic bacteria phenotypic and genetic virulence markers indicates that pathogenicity formation is based on a structural modification of bacterial DNA which is linked with migration of interbacterial pathogenicity «islands» genetic determinants. Structural organization features of these mobile genetic elements determine high expression probability, and PCR detection of pathogenicity «islands» determinants that control adhesins, invasins, cytotoxic and cytolitic toxines synthesis may indicate etiopathogenetic significance of clinical isolates.

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ГЕНЕТИЧЕСКИЕ МАРКЕРЫ ВИРУЛЕНТНОСТИ УСЛОВНО ПАТОГЕННЫХ БАКТЕРИЙ
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V. M Bondarenko

Gamaleya Research Institute of Epidemiology and Microbiology, Moscow, Russia

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