Email this article CLINICAL COURSE AND OUTCOMES OF INFLUENZA A (H1N1) 2009 IN PREGNANT WOMEN
- Authors: Tarbaeva D.A1, Kostinov M.P2, Iozefson S.A1, Zagorodnyaya E.D1
-
Affiliations:
- Chita State Medical Academy, Russia
- Mechnikov Research Institute of Vaccines and Sera, Moscow, Russia
- Issue: Vol 88, No 4 (2011)
- Pages: 71-76
- Section: Articles
- URL: https://microbiol.crie.ru/jour/article/view/13536
- ID: 13536
Cite item
Full Text
Abstract
Aim. Study of course of pregnancy, delivery, postpartum period and perinatal outcomes in pregnant women with influenza A (H1N1) 2009. Materials and methods. Course of pregnancy and outcomes in 16 women, who had influenza A (H1N1) 2009, were analyzed. Influenza A (H1N1) 2009 virus was detected by PCR. Results. Influenza A (H1N1) 2009 had a severe course and high rates of complications: pneumonia (100%), respiratory distress syndrome (25%), placental deficiency (100%). Most of the neonates (87%) from mothers, who had influenza A (H1N1) 2009, had neonatal period disorders: congenital pneumonia - 2 (12.5%), cerebral ischemia - 10 (62.5%), hyperbilirubinemia - 2 (12.5%), vegeto-visceral syndrome - 4 (25%), hemorrhagic, convulsive and respiratory distress syndrome - 1 (6.7%) each. Alteration in placenta was detected - influenza placentitis. Transplacental route of virus transmission was not detected. Conclusion. Pregnant women are a high risk group for influenza and serious complications caused by the virus. Influenza A (H1N1) 2009 has a more severe course and a higher rate of complications in both mothers and neonates.
About the authors
D. A Tarbaeva
Chita State Medical Academy, Russia
M. P Kostinov
Mechnikov Research Institute of Vaccines and Sera, Moscow, Russia
S. A Iozefson
Chita State Medical Academy, Russia
E. D Zagorodnyaya
Chita State Medical Academy, Russia
References
- Акушерство. Э.К. Айламазян и др. (ред.). М., 2007.
- Афанасьева О.И. и др. Клиническая характеристика гриппа у детей в современном мегаполисе. Дет. инф. 2009, 3: 10-13.
- Белан Ю.Б., Старикович М.В. Грипп А/California/2009 (H1N1) у детей. Лечащий врач. 2009, 10: 50-53.
- Деева Э.Г. Грипп. На пороге пандемии. М., ГЭОТАР-Медиа, 2008.
- Осидак Л.В. и др. Грипп как проблема XXI века. Дет. инф. 2009, 3: 3-9.
- Фисун А.Я. и др. Свиной грипп: эпидемиология, диагностика, лечение и профилактика. Военно-мед. журн. 2009, 7: 46-54.
- Шехтман М.М. Руководство по экстрагенитальной патологии у беременных. М., Триада-Х, 2008.
- Jamieson D.J., Honein M.A., Rasmussen S.A. et al. H1N1 2009 influenza virus infection during pregnancy in the USA. Lancet. 2009, 374: 451-458.
- Mangtani P., Mak T.K., Pfeifer D. Pandemic infection in pregnant women in the USA. Ibid. 2009, 374: 429-430.
- United States Centers for Disease Control and Prevention. Pregnant women and swine influenza: Considerations for Clinicians. http:// www.cdc.gov swineflu/ clinician_ pregnant. htm (Accessed May 3, 2009).
Supplementary files
