CLINICAL COURSE AND OUTCOMES OF INFLUENZA A (H1N1) 2009 IN PREGNANT WOMEN


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Abstract

Aim. Study of course of pregnancy, delivery, postpartum period and perinatal outcomes in pregnant women with influenza A (H1N1) 2009. Materials and methods. Course of pregnancy and outcomes in 16 women, who had influenza A (H1N1) 2009, were analyzed. Influenza A (H1N1) 2009 virus was detected by PCR. Results. Influenza A (H1N1) 2009 had a severe course and high rates of complications: pneumonia (100%), respiratory distress syndrome (25%), placental deficiency (100%). Most of the neonates (87%) from mothers, who had influenza A (H1N1) 2009, had neonatal period disorders: congenital pneumonia - 2 (12.5%), cerebral ischemia - 10 (62.5%), hyperbilirubinemia - 2 (12.5%), vegeto-visceral syndrome - 4 (25%), hemorrhagic, convulsive and respiratory distress syndrome - 1 (6.7%) each. Alteration in placenta was detected - influenza placentitis. Transplacental route of virus transmission was not detected. Conclusion. Pregnant women are a high risk group for influenza and serious complications caused by the virus. Influenza A (H1N1) 2009 has a more severe course and a higher rate of complications in both mothers and neonates.

About the authors

D. A Tarbaeva

Chita State Medical Academy, Russia

M. P Kostinov

Mechnikov Research Institute of Vaccines and Sera, Moscow, Russia

S. A Iozefson

Chita State Medical Academy, Russia

E. D Zagorodnyaya

Chita State Medical Academy, Russia

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Copyright (c) 2011 Tarbaeva D.A., Kostinov M.P., Iozefson S.A., Zagorodnyaya E.D.

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