STUDIES OF PROPERTIES OF PANDEMIC INFLUENZA VIRUS A/H1N1 CIRCULATED IN RUSSIAN FEDERATION IN 2009 — 2010


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Abstract

Aim. Studies of cultural, virologic, antigenic properties of 89 samples of pandemic influenza A(H1N1) 2009 virus isolated in Russian Federation from May 2009 to March 2010. Materials and methods. Properties of isolated samples were compared with those of the reference strain A/ California/04/2009 (H1N1). Results. Studies of biological properties and analysis of genome nucleotide sequences of the isolated samples showed that those strains are closely related to the reference strain. Conclusion. Monitoring of genetic, virologic and antigenic properties of pandemic influenza A(H1N1) 2009 virus isolates carried out from May 2009 to March 2010 did not reveal significant changes in the abovementioned properties of the virus or emergence of mutations that can lead to such changes.

About the authors

A. P Agafonov

State Scientific Center of Virology and Biotechnology «Vector», Koltsovo, Novosibirsk region, Russia

A. M Shestopalov

State Scientific Center of Virology and Biotechnology «Vector», Koltsovo, Novosibirsk region, Russia

A. N Shikov

State Scientific Center of Virology and Biotechnology «Vector», Koltsovo, Novosibirsk region, Russia

O. K Demina

State Scientific Center of Virology and Biotechnology «Vector», Koltsovo, Novosibirsk region, Russia

A. G Durymanov

State Scientific Center of Virology and Biotechnology «Vector», Koltsovo, Novosibirsk region, Russia

A. A Sergeev

State Scientific Center of Virology and Biotechnology «Vector», Koltsovo, Novosibirsk region, Russia

P. A Agafonova

State Scientific Center of Virology and Biotechnology «Vector», Koltsovo, Novosibirsk region, Russia

A. V Vinokurova

State Scientific Center of Virology and Biotechnology «Vector», Koltsovo, Novosibirsk region, Russia

K. A Sharshov

State Scientific Center of Virology and Biotechnology «Vector», Koltsovo, Novosibirsk region, Russia

S. A Berillo

State Scientific Center of Virology and Biotechnology «Vector», Koltsovo, Novosibirsk region, Russia

M. O Skarnovich

State Scientific Center of Virology and Biotechnology «Vector», Koltsovo, Novosibirsk region, Russia

A. O Sementsova

State Scientific Center of Virology and Biotechnology «Vector», Koltsovo, Novosibirsk region, Russia

B. A Ternovoy

State Scientific Center of Virology and Biotechnology «Vector», Koltsovo, Novosibirsk region, Russia

E. M Malkova

State Scientific Center of Virology and Biotechnology «Vector», Koltsovo, Novosibirsk region, Russia

E. A Stavsky

State Scientific Center of Virology and Biotechnology «Vector», Koltsovo, Novosibirsk region, Russia

I. G Drozdov

State Scientific Center of Virology and Biotechnology «Vector», Koltsovo, Novosibirsk region, Russia

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Copyright (c) 2011 Agafonov A.P., Shestopalov A.M., Shikov A.N., Demina O.K., Durymanov A.G., Sergeev A.A., Agafonova P.A., Vinokurova A.V., Sharshov K.A., Berillo S.A., Skarnovich M.O., Sementsova A.O., Ternovoy B.A., Malkova E.M., Stavsky E.A., Drozdov I.G.

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