Email this article PHENOTYPIC CHARACTERISTIC OF STAPHYLOCOCCI AND LOCAL IMMUNITY DURING BACTERIAL CARRIAGE
- Authors: Kartashova O.L1,2, Norkina A.S1,2, Chaynikova I.N1,2, Smolyagin A.I1,2
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Affiliations:
- Institute of Cellular and Intracellular Symbiosis, Orenburg
- Orenburg State Medical Academy, Russia
- Issue: Vol 86, No 4 (2009)
- Pages: 99-103
- Section: Articles
- Submitted: 09.06.2023
- Published: 15.08.2009
- URL: https://microbiol.crie.ru/jour/article/view/13390
- ID: 13390
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Abstract
Aim. To assess prevalence and intensity of antilactoferrin and sIgA-protease activity in strains of staphylococci and to study the state of local immunity in resident and transitory bacterial carriers. Materials and methods. Strains of Staphylococcus aureus and S.epidermidis isolated from 67 healthy persons, who were tested for staphylococcal carriage with subsequent differentiation of types of carriage according to Chistovitch's method, were studied. Antilactoferrin and sIgA-protease activity as well as levels of lactoferrin and sIgA in nasal secretions were determined using fluoroimmunoassay. Results. Higher prevalence as well as intensity of antilactoferrin and sIgA-protease activity and combination of these characteristics was determined for strains of S.aureus from resident carriers compared with strains from transitory carriers. Higher levels of lactoferrin and sIgA were observed in nasal secretions of resident carriers compared with transitory carriers. Conclusion. Studied factors could be the markers of resident type of carriage that should be considered for the development of effective measures for sanation in persons with prolonged bacterial carriage.
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ФЕНОТИПИЧЕСКАЯ ХАРАКТЕРИСТИКА СТАФИЛОКОККОВ И МЕСТНЫЙ ИММУНИТЕТ ПРИ БАКТЕРИОНОСИТЕЛЬСТВЕ×
About the authors
O. L Kartashova
Institute of Cellular and Intracellular Symbiosis, Orenburg; Orenburg State Medical Academy, Russia
A. S Norkina
Institute of Cellular and Intracellular Symbiosis, Orenburg; Orenburg State Medical Academy, Russia
I. N Chaynikova
Institute of Cellular and Intracellular Symbiosis, Orenburg; Orenburg State Medical Academy, Russia
A. I Smolyagin
Institute of Cellular and Intracellular Symbiosis, Orenburg; Orenburg State Medical Academy, Russia
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