CHARACTERISTICS OF MICROECOLOGICAL DISTURBANCES DURING ENDOMETRITIS

Aim. To study the state of vaginal microbiocenosis in women with endometritis and to assess association between microecological disturbances and characteristic of clinical course of the disease. Materials and methods. Two hundred women of childbearing age with endometritis were studied, of which 83 had acute form of the disease, and 117 — chronic form. Control group was comprised by 30 clinically healthy women. Antilysozyme, anticomplement, and antilactoferrin activities were determined in isolated and identified microorganisms. Microecological disturbances in vaginal biotope were determined applying criteria proposed by Sokolova K.Ya. et al. and Amsel R. et al. Results. Microecological disturbances in vaginal biotope were revealed on women with endometritis — in particular, bacterial vaginosis, deficiency of dominant microflora (lactobacilli), and the presence of associate microorganisms with clearly expressed persistence characteristics. On the background

vaginal microbiocenosis, microecological disturbances, factors of persistence, endometritis, women's reproductive tract