MECHANISMS OF CHLAMYDIA TRACHOMATIS AND HERPES SIMPLEX VIRUS PERSISTENCE DURING VIRAL-BACTERIAL INFECTION


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Abstract

Possible mechanisms of persistence on the example of Chlamydia trachomatis in conditions of herpes simplex virus type 2 (HSV-2) superinfection in vitro and in vivo are described. Emergence of persisting forms of Chlamydia as well as factors influencing on this process are considered. Contemporary views on pathogenesis of viralbacterial infection with HSV-2 and C.trachomatis as well as interactions of the agents with local immunity factors are described. It was suggested that there are signaling pathways through which HSV-2 changes life cycle of Chlamydia .

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МЕХАНИЗМЫ ПЕРСИСТЕНЦИИ CHLAMYDIA TRACHOMATIS И ВИРУСА ПРОСТОГО ГЕРПЕСА ПРИ ВИРУСНО-БАКТЕРИАЛЬНОЙ ИНФЕКЦИИ
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About the authors

V. A Bekhalo

Gamaleya Research Institute of Epidemiology and Microbiology, Moscow, Russia

E. V Sysolyatina

Gamaleya Research Institute of Epidemiology and Microbiology, Moscow, Russia

E. V Nagurskaya

Gamaleya Research Institute of Epidemiology and Microbiology, Moscow, Russia

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Copyright (c) 2009 Bekhalo V.A., Sysolyatina E.V., Nagurskaya E.V.

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