DELAYED RESULTS OF VACCINATION OF CHILDREN WITH RECURRENT RESPIRATORY INFECTIONS AGAINST MEASLES AND MUMPS


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Abstract

Aim. Assessment of results of immunization against measles and mumps in children with recurrent respiratory infections. Materials and methods. Levels of IgG against measles and mumps viruses were measured using enzyme immunoassay. Two hundred and twelve serum samples obtained from 6 groups of children with 20 — 45 persons (boys and girls) in each were tested. Children of various ages were presented in each group. Also, immunologic parameters were measured in all children. Results. It was established that mean antibody titers to measles and mumps viruses did not change during 10 years. In more than 50% of children correlation between high and low titers of antibodies of different specificity was found. Conclusion. Recurrent respiratory illnesses determine complex regulation of transition of memory cells into cells secreting antibodies to measles and mumps viruses.

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ОТСРОЧЕННЫЕ РЕЗУЛЬТАТЫ ВАКЦИНАЦИИ ЧАСТО БОЛЕЮЩИХ ДЕТЕЙ ПРОТИВ КОРИ И ЭПИДЕМИЧЕСКОГО ПАРОТИТА
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About the authors

V. A Lyashenko

Mechnikov Research Institute of Vaccines and Sera, Moscow, Russia

L. I Krasnoproshina

Mechnikov Research Institute of Vaccines and Sera, Moscow, Russia

C. K Alexander

Mechnikov Research Institute of Vaccines and Sera, Moscow, Russia

S. A Skhodov

Mechnikov Research Institute of Vaccines and Sera, Moscow, Russia

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Copyright (c) 2010 Lyashenko V.A., Krasnoproshina L.I., Alexander C.K., Skhodov S.A.

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