Email this article ANTIMICROBIAL AND ANTIFUNGAL ACTIVITY OF LICHENS PREVALENT IN BELARUS
- Authors: Tapalsky D.V.1, Petrenev D.R.2, Khramchenkova O.M.3, Doroshkevich A.S.1
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Affiliations:
- Gomel State Medical University
- Institute of Radiobiology of the National Academy of Sciences of Belarus
- Gomel State University
- Issue: Vol 94, No 2 (2017)
- Pages: 60-65
- Section: ORIGINAL RESEARCHES
- URL: https://microbiol.crie.ru/jour/article/view/143
- DOI: https://doi.org/10.36233/0372-9311-2017-2-60-65
- ID: 143
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Abstract
Aim. Study spectrum and expressiveness of antibacterial and antifungal properties oflichen extracts. Materials and methods. Antimicrobial activity of acetone extracts from Hypogymnia physodes, Xanthoria parietina, Evernia prunastri, Ramalina pollinaria, Cladonia arbuscula lichens was determined by micro-dilution methods in broth for 4 - 500 mcg/ml concentrations against 13 strains from ATCC collection and 6 clinical isolates. Results. High antibacterial activity of H. physodes and C. arbuscular extracts against staphylococci and enterococci was detected (MIC 31 - 62 mcg/ml). Antimicrobial activity against enterobacteria and Pseudomonas aeruginosa was absent for all the extracts. E.prunastri, H.physodes and C arbuscula extracts were active against Stenotrophomonas maltophilia strains (MIC 250 - 500 mcg/ml). Antifungal activity (MIC 500 mcg/ml for 4 Candida strains) was only detected for the E. prunastri extract. Conclusion. H.physodes and C. arbuscula lichens can be examined as a perspective source of antibacterial substances, effective against antibiotics resistant staphylococci, streptococci and S. maltophilia strains.
About the authors
D. V. Tapalsky
Gomel State Medical University
Author for correspondence.
Email: noemail@neicon.ru
Russian Federation
D. R. Petrenev
Institute of Radiobiology of the National Academy of Sciences of Belarus
Email: noemail@neicon.ru
Russian Federation
O. M. Khramchenkova
Gomel State University
Email: noemail@neicon.ru
Russian Federation
A. S. Doroshkevich
Gomel State Medical University
Email: noemail@neicon.ru
Russian Federation
References
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- Boustie J., Grube M. Lichens - a promising source of bioactive secondary metabolites. Plant. Genet. Resour. 2005, 3: 273-278.
- Chang Y.T., Lin C.Y., Chen Y.H., Hsueh P.R. Update on infections caused by Stenotrophomonas maltophilia with particular attention to resistance mechanisms and therapeutic options. Front. Microbiol. 2015, 6: 893.
- Grujicic D., Stosic I., Kosanic M. et al. Evaluation of in vitro antioxidant, antimicrobial, genotoxic and anticancer activities of lichen Cetraria islandica. Cytotechnology. 2014, 66 (5): 803-813.
- Gulluce M., Aslan A., Sokmen M. et al. Screening the antioxidant and antimicrobial properties of the lichens Parmelia saxatilis, Platismatia glauca, Ramalina pollinaria, Ramalina polymorpha and Umbilicaria nylanderiana. Phytomedicine. 2006, 13 (7): 515521.
- Kosanic M., Manojlovic N., Jankovic S. et al. Evernia prunastri and Pseudoevernia fur-furaceae lichens and their major metabolites as antioxidant, antimicrobial and anticancer agents. Food. Chem. Toxicol. 2013, 53:112-118.
- Kosanic M., Rankovic B., Stanojkovic T et al. Biological activities and chemical composition of lichens from Serbia. EXCLI J. 2014, 13:1226-1238.
- Mitrovic T, Stamenkovic S., Cvetkovic V. et al. Platismatia glaucia and Pseudevernia furfuracea lichens as sources of antioxidant, antimicrobial and antibiofilm agents. EXCLI J. 2014, 13: 938-953.
- Oksanen I. Ecological and biotechnological aspects oflichens. Appl. Microbiol. Biotechnol. 2006, 73 (4): 723-734.
- Rankovic B., Misic M., Sukdolak S. Antimicrobial activity of extracts of the lichens Cladonia furcata, Parmelia caperata, Parmelia pertusa, Hypogymnia physodes and Umbilicaria polyphylla. Br. J. Biomed. Sci. 2007, 64 (4): 143-148.
- Studzinska-Sroka E., Holderna-Kedzia E., Galanty A. et al. In vitro antimicrobial activity of extracts and compounds isolated from Cladonia uncialis. Nat. Prod. Res. 2015; 29 (24): 2302-2307.
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