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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Journal of microbiology, epidemiology and immunobiology</journal-id><journal-title-group><journal-title xml:lang="en">Journal of microbiology, epidemiology and immunobiology</journal-title><trans-title-group xml:lang="ru"><trans-title>Журнал микробиологии, эпидемиологии и иммунобиологии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0372-9311</issn><issn publication-format="electronic">2686-7613</issn><publisher><publisher-name xml:lang="en">Central Research Institute for Epidemiology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">55</article-id><article-id pub-id-type="doi">10.36233/0372-9311-2016-3-88-97</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">ROLE OF BIOFILMS IN SURVIVAL AND PRESERVATION OF VIRULENCE OF CHOLERA VIBRIOS IN THE ENVIRONMENT AND HUMAN ORGANISM</article-title><trans-title-group xml:lang="ru"><trans-title>РОЛЬ БИОПЛЕНОК В ВЫЖИВАЕМОСТИ И СОХРАНЕНИИ ВИРУЛЕНТНОСТИ ХОЛЕРНЫХ ВИБРИОНОВ В ОКРУЖАЮЩЕЙ СРЕДЕ И ОРГАНИЗМЕ ЧЕЛОВЕКА</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Titova</surname><given-names>S. V.</given-names></name><name xml:lang="ru"><surname>Титова</surname><given-names>С. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Alekseeva</surname><given-names>L. P.</given-names></name><name xml:lang="ru"><surname>Алексеева</surname><given-names>Л. П.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Andrusenko</surname><given-names>I. T.</given-names></name><name xml:lang="ru"><surname>Андрусенко</surname><given-names>И. Т.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Rostov-on-Don Institute for Plague Control</institution></aff><aff><institution xml:lang="ru">Ростовский-на-Дону противочумный институт</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2016-06-28" publication-format="electronic"><day>28</day><month>06</month><year>2016</year></pub-date><volume>93</volume><issue>3</issue><issue-title xml:lang="ru"/><fpage>88</fpage><lpage>97</lpage><history><date date-type="received" iso-8601-date="2019-04-10"><day>10</day><month>04</month><year>2019</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2016, Titova S.V., Alekseeva L.P., Andrusenko I.T.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2016, Титова С.В., Алексеева Л.П., Андрусенко И.Т.</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="en">Titova S.V., Alekseeva L.P., Andrusenko I.T.</copyright-holder><copyright-holder xml:lang="ru">Титова С.В., Алексеева Л.П., Андрусенко И.Т.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://microbiol.crie.ru/jour/article/view/55">https://microbiol.crie.ru/jour/article/view/55</self-uri><abstract xml:lang="en"><p>Materials regarding biofilms of cholera vibrios are presented. Formation of biofilms is shown to be a significant pathogenicity factor and one of the main strategies, increasing survival of cholera vibrios in human organism and the environment.</p></abstract><trans-abstract xml:lang="ru"><p>Представлены материалы относительно биопленок холерных вибрионов. Показано, что формирование биопленок является существенным фактором патогенности и одной из основных стратегий, повышающих выживание холерных вибрионов в организме человека и в окружающей среде.</p></trans-abstract><kwd-group xml:lang="en"><kwd>cholera vibrios</kwd><kwd>biofilm</kwd><kwd>environment</kwd><kwd>human intestine</kwd><kwd>pathogenicity factors</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>холерные вибрионы</kwd><kwd>биопленка</kwd><kwd>окружающая среда</kwd><kwd>кишечникчеловека</kwd><kwd>факторы патогенности</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Блинкова Л.П. Перспективы использования бактериоцинов для профилактики и терапии инфекций. Журн. микробиол. 1984, 5: 10-15.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Голубев Б.П. Экологические аспекты распространения вибрионов Эльтор в объектах окружающей среды. Автореф. дис. канд. мед. наук. Саратов, 1993.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Лахтин В.М., Алешкин В.А., Лахтин М.В. и др. Лектины, адгезины и лектиновые вещества лактобацилл и бифидобактерий. Вестник РАМН. 2006, 1: 28-34.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Маркина О.В., Шелохович А.И., Терентьев А.Н. и др. Стабилизированные фазовые варианты Vibrio cholerae El Tor P-18895. В: Холера и патоген, для человека вибрионы. Ростов-на-Дону, Дониздат, 2014, 27: 112-114.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Мишанькин Б.Н., Дуванова О.В., Романова Л.В. и др. Мембранный белок ОтрТ холерного вибриона как возможный представитель омптинов семейства Vibrionaceae. Проблемы особо опасных инфекций. 2014, 3: 52-56.</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Мишанькин Б.Н., ШиманюкН.Я., Водопьянов С.О. идр. Изучение хитинолитического комплекса холерного вибриона сероварианта 0139. Биотехнология. 2010, 1: 32-40.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Мишанькин Б.Н., Дуванова О.В., Шипко Е.С. и др. Система активации плазминогена у Vibrio cholerae. Журн. микробиол. 2013, 5: 13-20.</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Сизова Ю.В., Черепахина И.Я., Балахнова В.В. идр. Вариабельность свойств, характеризующих способность к выживанию холерных вибрионов в биопленочных сообществах. Пробл. особо опасных инф. 2012, 3 (113): 54-57.</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>ШиманюкН.Я., Дуванова, О.В., Сучков И.Ю. идр. Нейраминидаза Vibrio cholerae 0139 «Бенгал»: обнаружение, очистка и некоторые свойства. Биотехнология, 1999, 3: 56-62.</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Augustine N., Peter A.W., Kerkar S., Thomas S. Arctic actinomycetes as potential inhibitors of Vibrio cholerae biofilm. Curr. Microbiol. 2012, 64 (4): 338-342.</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Berk V., Fong J.C., Dempsey G.T. et al. Molecular architecture and assembly principles of Vibrio cholerae biofilms. Science. 2012, 337 (6091): 236-239.</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Blokesch M. Chitin colonization, chitin degradation and chitin-induced natural competence of Vibrio cholerae are subject to catabolite repression. Environ. Microbiol. 2012, 14 (8): 1898-1912.</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>Boyhan S., Beyhan S., Tischler A.D. et al. Transcriptome and phenotypic responses of Vibrio cholerae to increased cyclic di-GMP level. J. Bacteriol. 2006, 188 (10): 3600-3613.</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>Castro-Rosas J., Escartin, E.F. Increased toleranceof Vibrio cholerae 01 to temperature, pH, or dryingassociated with colonization of shrimp carapaces. Int. J. Food Microbiol. 2005,102: 195-201.</mixed-citation></ref><ref id="B15"><label>15.</label><mixed-citation>Costerton J.W., Stewart P.S., Greenberg E.P. Bacterial biofilms: a common cause of persistentinfections. Science. 1999, 284: 1318-1322.</mixed-citation></ref><ref id="B16"><label>16.</label><mixed-citation>Emch M., Feldacker C., Yunus M. et al. Effects of global climate on infectious disease: the cholera model. Am. J. Trap. Med. Hyg. 2008, 78: 823-832.</mixed-citation></ref><ref id="B17"><label>17.</label><mixed-citation>Faruque S.M., Albert M.J., Mekalanos J.J. Epidemiology, genetics, and ecology of toxigenic Vibrio cholera. Microbiol. Mol. Biol. Rev. 1998, 62 (4): 1301-1314.</mixed-citation></ref><ref id="B18"><label>18.</label><mixed-citation>Faruque S.M., Biswas K., Udden S.M. etal. Transmissibility of cholera: in vivo-formed biofilms and their relationship to infectivity and persistence in the environment. Proc. Nat. Acad. Sci. USA. 2006, 103 (16): 6350-6355.</mixed-citation></ref><ref id="B19"><label>19.</label><mixed-citation>Franklin A., Soderlind O., Mollby R. Plasmids coding for enterotoxins, K88 antigen and colicins in porcine Escherichia coli strains of O-group 149. Med. Microbiol. Immunol. 1981,170:63-72.</mixed-citation></ref><ref id="B20"><label>20.</label><mixed-citation>Giglio K.M., Fong J.C., Yildiz F.H., Sondermann H. Structural basis for biofilm formation via the Vibrio cholerae matrix protein RbmA. J. Bacteriol. 2013, 195 (14): 3277-3286.</mixed-citation></ref><ref id="B21"><label>21.</label><mixed-citation>Gillor O., Kirkur B.C., Riley M.A. Colicins and microcins: the next generation antimimicro-bials. Adv. Appl. Microbiol. 2004, 54: 129-146.</mixed-citation></ref><ref id="B22"><label>22.</label><mixed-citation>Gopalakrishnan S., Durai M., Kitchens K. et al. Larazotide acetate regulates epithelial tight junctions in vitro and in vivo. Peptides. 2012, 35 (1): 86-94.</mixed-citation></ref><ref id="B23"><label>23.</label><mixed-citation>Hartley D.M., Morris J.M., Smith D.L. Hyperinfectivity: a critical element in the ability ofV. cholerae to cause epidemics? PLoS. Med. 2006, 3 (1): e7.</mixed-citation></ref><ref id="B24"><label>24.</label><mixed-citation>Islam M.S., Drasar B.S., Bradley D.J. Survival of toxigenic Vibrio cholerae 01 with a common duckweed, Lemna minor, in artificial aquatic ecosystems. Trans. R. Soc. Trop. Med. Hyg. 1990, 84 (3): 422-424.</mixed-citation></ref><ref id="B25"><label>25.</label><mixed-citation>Kaplan J.B., Ragunath C., Ramasubbu N., Fine D.H. Detachment of Actinobacillus actinomycetemcomitans biofilm cells by an endogenous (5-hexosaminidase activity. J. Bacteriol. 2003, 185 (16): 4693-4698.</mixed-citation></ref><ref id="B26"><label>26.</label><mixed-citation>Maestre-Reyna M., Wu W.J., Wang A.H. Structural insights into RbmA, a biofilm scaffolding protein ofV. cholerae. PLoS One. 2013, 8 (12): e82458.</mixed-citation></ref><ref id="B27"><label>27.</label><mixed-citation>Moorthy S., Watnic P.I. Genetic evidence that the Vibrio cholerae monolayer is a distinct stage in biofilm development. Mol. Microbiol. 2004, 52 (2): 573-587.</mixed-citation></ref><ref id="B28"><label>28.</label><mixed-citation>Mudrak B., Tamayo R. The Vibrio cholerae Pst2 phosphate transport system is upregulated in biofilms and contributes to biofilm-induced hyperinfectivity. Infect. Immun. 2012, 80 (5): 1794-1802.</mixed-citation></ref><ref id="B29"><label>29.</label><mixed-citation>Olivier V, Queen J., Satchell K.J.F Successful small intestine colonization of adult mice by Vibrio cholerae requires ketamine anesthesia and accessory toxins. PLoS One. 2009, 4 (10): e7352.</mixed-citation></ref><ref id="B30"><label>30.</label><mixed-citation>Parker Z.M., Pendergraft S.S., Sobieraj J. et al. Elevated levels ofthe norspermidine synthesis enzyme NspC enhance Vibrio cholerae biofilm formation without affecting intracellular norspermidine concentrations. Expert Rev. Gastroenterol. Hepatol. 2012, 6 (1): 17-23.</mixed-citation></ref><ref id="B31"><label>31.</label><mixed-citation>Purdy A.E., Watnick P.I. Spatially selective colonization of the arthropod intestine through activation of Vibrio cholerae biofilm formation. Proc. Nat. Acad. Sci. USA. 2011, 108 (49): 19737-19742.</mixed-citation></ref><ref id="B32"><label>32.</label><mixed-citation>Ray V.A., Morris A.R., Visick K.L. A semi-quantitative approach to assess biofilm formation using wrinkled colony development. J. Vis. Exp. 2012, 64: pii-4035.</mixed-citation></ref><ref id="B33"><label>33.</label><mixed-citation>Seper A., Fengler V.H., Roier S. et al. Extracellular nucleases and extracellular DNA play important roles in Vibrio cholerae biofilm formation. Mol. Microbiol. 2011, 82 (4): 1015-1037.</mixed-citation></ref><ref id="B34"><label>34.</label><mixed-citation>Spagnuolo M.A., Dirita V, Kirschner D. A model for Vibrio cholerae colonization of the human intestine. J. Theor. Biol. 2011, 289: 247-258.</mixed-citation></ref><ref id="B35"><label>35.</label><mixed-citation>Suckow G., Seitz P., Blokesch M. Quorum sensing contributes to natural transformation of Vibrio cholerae in a species-specific manner. J. Bacteriol. 2011, 193 (18): 4914-4924.</mixed-citation></ref><ref id="B36"><label>36.</label><mixed-citation>Tamayo R., Pratt J.T., Camilli A. Roles of cyclic diguanylate in the regulation of bacterial pathogenesis. Annual Rev. Microbiol. 2007, 61: 131-148.</mixed-citation></ref><ref id="B37"><label>37.</label><mixed-citation>Tamayo R., PatimallaB., Camilli A. Growth in a biofilm induces a hyperinfectious phenotype in Vibrio cholerae. Infect. Immun. 2010, 78 (8): 3560-3569.</mixed-citation></ref><ref id="B38"><label>38.</label><mixed-citation>Valeru S.P., Wai S.N., Saeed A. et al. ToxR of Vibrio cholerae affects biofilm, rugosity and survival with Acanthamoeba castellanii. BMC Res. Notes. 2012, 5 (1): 33.</mixed-citation></ref><ref id="B39"><label>39.</label><mixed-citation>Watnick P.I., Kolter R. Steps in the development of a Vibrio cholerae El Tor biofilm. Mol. Microbiol. 1999, 34: 586-595.</mixed-citation></ref><ref id="B40"><label>40.</label><mixed-citation>Zettler Erik R., Tracy J. Mincer, Linda A. Amaral-Zettler. Life in the «Plastisphere»: Microbial communities on plastic marine debris. Envir. Sci.Technol. 2013, 47 (13): 7137-7146.</mixed-citation></ref></ref-list></back></article>
