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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Journal of microbiology, epidemiology and immunobiology</journal-id><journal-title-group><journal-title xml:lang="en">Journal of microbiology, epidemiology and immunobiology</journal-title><trans-title-group xml:lang="ru"><trans-title>Журнал микробиологии, эпидемиологии и иммунобиологии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0372-9311</issn><issn publication-format="electronic">2686-7613</issn><publisher><publisher-name xml:lang="en">Central Research Institute for Epidemiology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">363</article-id><article-id pub-id-type="doi">10.36233/0372-9311-2019-3-54-59</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>ORIGINAL RESEARCHES</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">The application of molecular genetic analysis and genomic profiling of infectious diseases causative agents in Sochi during the preparation and holding of the Fifa World Cup 2018</article-title><trans-title-group xml:lang="ru"><trans-title>Применение молекулярно-генетического анализа и геномного профилирования возбудителей инфекционных болезней региона Сочи в период подготовки и проведения чемпионата мира по футболу FIFA-2018</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Popova</surname><given-names>A. Yu.</given-names></name><name xml:lang="ru"><surname>Попова</surname><given-names>А. Ю.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Moscow</p></bio><bio xml:lang="ru"><p>Москва</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kulichenko</surname><given-names>A. N.</given-names></name><name xml:lang="ru"><surname>Куличенко</surname><given-names>А. Н.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Volynkina</surname><given-names>A. S.</given-names></name><name xml:lang="ru"><surname>Волынкина</surname><given-names>А. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="ru"><p>Волынкина Анна Сергеевна</p><p>355035, Ставрополь, ул. Советская, 13-15, р.т. (8652)26-03-12</p></bio><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kuznetsova</surname><given-names>I. V.</given-names></name><name xml:lang="ru"><surname>Кузнецова</surname><given-names>И. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Podkolzin</surname><given-names>A. T.</given-names></name><name xml:lang="ru"><surname>Подколзин</surname><given-names>А. Т.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Moscow</p></bio><bio xml:lang="ru"><p>Москва</p></bio><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Chekhvalova</surname><given-names>E. V.</given-names></name><name xml:lang="ru"><surname>Чехвалова</surname><given-names>Е. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff4"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Orobey</surname><given-names>V. G.</given-names></name><name xml:lang="ru"><surname>Оробей</surname><given-names>В. Г.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff5"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing</institution></aff><aff><institution xml:lang="ru">Федеральная служба по надзору в сфере защиты прав потребителей и благополучия человека</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Stavropol Research Institute for Plague Control</institution></aff><aff><institution xml:lang="ru">Ставропольский противочумный институт</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">Central Research Institute of Epidemiology</institution></aff><aff><institution xml:lang="ru">Центральный НИИ эпидемиологии</institution></aff></aff-alternatives><aff-alternatives id="aff4"><aff><institution xml:lang="en">Center of Hygiene and Epidemiology in Krasnodar Territory (Sochi Branch)</institution></aff><aff><institution xml:lang="ru">Сочинский филиал Центра гигиены и эпидемиологии в Краснодарском крае</institution></aff></aff-alternatives><aff-alternatives id="aff5"><aff><institution xml:lang="en">Territorial Department of Rospotrebnadzor in Krasnodar Territory</institution></aff><aff><institution xml:lang="ru">Территориальный отдел Управления Роспотребнадзора по Краснодарскому краю в г. Сочи</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2019-08-22" publication-format="electronic"><day>22</day><month>08</month><year>2019</year></pub-date><volume>96</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>54</fpage><lpage>59</lpage><history><date date-type="received" iso-8601-date="2019-08-21"><day>21</day><month>08</month><year>2019</year></date><date date-type="accepted" iso-8601-date="2019-08-21"><day>21</day><month>08</month><year>2019</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2019, Popova A.Y., Kulichenko A.N., Volynkina A.S., Kuznetsova I.V., Podkolzin A.T., Chekhvalova E.V., Orobey V.G.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2019, Попова А.Ю., Куличенко А.Н., Волынкина А.С., Кузнецова И.В., Подколзин А.Т., Чехвалова Е.В., Оробей В.Г.</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="en">Popova A.Y., Kulichenko A.N., Volynkina A.S., Kuznetsova I.V., Podkolzin A.T., Chekhvalova E.V., Orobey V.G.</copyright-holder><copyright-holder xml:lang="ru">Попова А.Ю., Куличенко А.Н., Волынкина А.С., Кузнецова И.В., Подколзин А.Т., Чехвалова Е.В., Оробей В.Г.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://microbiol.crie.ru/jour/article/view/363">https://microbiol.crie.ru/jour/article/view/363</self-uri><abstract xml:lang="en"><p>During the preparation of the FIFA World Cup 2018 in 2015-2017 genetic features of regional pathogenic strains in the city of Sochi are determined. The strains and nucleic acid isolates of bacterial and viral infectious diseases causative agents — acute intestinal infections: rota-, noro-, astro and enteroviruses, Salmonella enteritidis, natural focal infections: hantaviruses, Rickettsia of tick spotted fevers group, Borrelia are genotyped. In result, complex genetic profiling of infection diseases causative agents variants that are actual for the Sochi region has been carried out. The obtained database was used to provide molecular analysis of pathogens during the XIX International Festival of Youth and Students (2017) and during the FIFA World Cup (2018). The perspective of using this algorithm of genetic analysis in description of outbreaks (cases) of infectious diseases in specific areas is shown.</p></abstract><trans-abstract xml:lang="ru"><p>При подготовке к проведению чемпионата мира по футболу FIFA-2018 в 2015-2017 гг. определены генетические особенности региональных штаммов-патогенов в г. Сочи. Типированы штаммы и изоляты нуклеиновых кислот возбудителей инфекционных болезней бактериальной и вирусной природы — ОКИ: рота-, норо-, астро и энтеровирусов, Salmonella enteritidis, природноочаговых инфекций: хантавирусов, риккетсий группы КПЛ, боррелий. В результате осуществлено комплексное генетическое профилирование актуальных для региона г. Сочи вариантов возбудителей инфекций. Полученная база данных использована для обеспечения молекулярного анализа штаммов-патогенов в период проведения XIX Международного фестиваля молодежи и студентов (2017 г.) и во время проведения чемпионата мира по футболу (2018 г.). Показана перспектива использования данного алгоритма генетического анализа при расшифровке вспышек (случаев) инфекционных болезней на конкретных территориях.</p></trans-abstract><kwd-group xml:lang="en"><kwd>molecular genetic analysis</kwd><kwd>acute intestinal infections</kwd><kwd>natural focal infections</kwd><kwd>FIFA World Cup 2018</kwd><kwd>Sochi</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>молекулярно-генетический анализ</kwd><kwd>острые кишечные инфекции</kwd><kwd>природноочаговые инфекции</kwd><kwd>чемпионат мира по футболу</kwd><kwd>Сочи</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>1.	Куличенко А.Н., Волынкина А.С., Лисицкая Я.В., Котенев Е.С., Кузнецова И.В., Подколзин А.Т, Зайцева Е.В., Паркина Н.В., Оробей В.Г Генетическое профилирование актуальных для региона г.-к. Сочи возбудителей природно-очаговых и кишечных инфекций. 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