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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Journal of microbiology, epidemiology and immunobiology</journal-id><journal-title-group><journal-title xml:lang="en">Journal of microbiology, epidemiology and immunobiology</journal-title><trans-title-group xml:lang="ru"><trans-title>Журнал микробиологии, эпидемиологии и иммунобиологии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0372-9311</issn><issn publication-format="electronic">2686-7613</issn><publisher><publisher-name xml:lang="en">Central Research Institute for Epidemiology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">237</article-id><article-id pub-id-type="doi">10.36233/0372-9311-2017-6-105-113</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">EPIDEMIC ANALYSIS ON CHOLERA IN AFRICA AND PROBLEMS OF PROFILAXIS</article-title><trans-title-group xml:lang="ru"><trans-title>ЭПИДЕМИОЛОГИЧЕСКИЙ АНАЛИЗ СИТУАЦИИ ПО ХОЛЕРЕ НА ТЕРРИТОРИИ АФРИКИ И ПРОБЛЕМЫ ПРОФИЛАКТИКИ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Karnaukhov</surname><given-names>I. G.</given-names></name><name xml:lang="ru"><surname>Карнаухов</surname><given-names>И. Г.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Cheldyshova</surname><given-names>N. B.</given-names></name><name xml:lang="ru"><surname>Челдышова</surname><given-names>Н. Б.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Grazhdanov</surname><given-names>A. K.</given-names></name><name xml:lang="ru"><surname>Гражданов</surname><given-names>А. К.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Krizky</surname><given-names>A. A.</given-names></name><name xml:lang="ru"><surname>Крицкий</surname><given-names>А. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Zadnova</surname><given-names>S. P.</given-names></name><name xml:lang="ru"><surname>Заднова</surname><given-names>С. П.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kedrova</surname><given-names>O. V.</given-names></name><name xml:lang="ru"><surname>Кедрова</surname><given-names>О. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Ivanova</surname><given-names>A. V.</given-names></name><name xml:lang="ru"><surname>Иванова</surname><given-names>А. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Toporkov</surname><given-names>V. P.</given-names></name><name xml:lang="ru"><surname>Топорков</surname><given-names>В. П.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Smirnova</surname><given-names>N. I.</given-names></name><name xml:lang="ru"><surname>Смирнова</surname><given-names>Н. И.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Boiro</surname><given-names>A. ..</given-names></name><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name><surname>Boumbali</surname><given-names>S. ..</given-names></name><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name><surname>Boiro</surname><given-names>M. Y.</given-names></name><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kutyrev</surname><given-names>V. V.</given-names></name><name xml:lang="ru"><surname>Кутырев</surname><given-names>В. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Russian Research Institute for Plague Control «Microb»</institution></aff><aff><institution xml:lang="ru">Российский научно-исследовательский противочумный институт «Микроб»</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Institute of Applied Biology</institution></aff><aff><institution xml:lang="ru">Исследовательский институт прикладной биологии Гвинеи</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2017-12-28" publication-format="electronic"><day>28</day><month>12</month><year>2017</year></pub-date><volume>94</volume><issue>6</issue><issue-title xml:lang="ru"/><fpage>105</fpage><lpage>113</lpage><history><date date-type="received" iso-8601-date="2019-04-10"><day>10</day><month>04</month><year>2019</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2017, Karnaukhov I.G., Cheldyshova N.B., Grazhdanov A.K., Krizky A.A., Zadnova S.P., Kedrova O.V., Ivanova A.V., Toporkov V.P., Smirnova N.I., Boiro A..., Boumbali S..., Boiro M.Y., Kutyrev V.V.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2017, Карнаухов И.Г., Челдышова Н.Б., Гражданов А.К., Крицкий А.А., Заднова С.П., Кедрова О.В., Иванова А.В., Топорков В.П., Смирнова Н.И., Boiro A..., Boumbali S..., Boiro M.Y., Кутырев В.В.</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="en">Karnaukhov I.G., Cheldyshova N.B., Grazhdanov A.K., Krizky A.A., Zadnova S.P., Kedrova O.V., Ivanova A.V., Toporkov V.P., Smirnova N.I., Boiro A..., Boumbali S..., Boiro M.Y., Kutyrev V.V.</copyright-holder><copyright-holder xml:lang="ru">Карнаухов И.Г., Челдышова Н.Б., Гражданов А.К., Крицкий А.А., Заднова С.П., Кедрова О.В., Иванова А.В., Топорков В.П., Смирнова Н.И., Boiro A..., Boumbali S..., Boiro M.Y., Кутырев В.В.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://microbiol.crie.ru/jour/article/view/237">https://microbiol.crie.ru/jour/article/view/237</self-uri><abstract xml:lang="en"><p>Presently Africa is one of the most affected regions of the world as regards cholera. More than 55 000 people are infected every year. The review contains the data on comparative assessment of epidemic manifestations associated with the current pandemic, caused by Vibrio cholerae biovar El Tor, and the preceding six pandemics, the agent of which was cholera vibrios of classical biovar. Studied have been the factors of large-scale cholera dissemination in Africa in the modern period and problems of its prophylaxis.</p></abstract><trans-abstract xml:lang="ru"><p>В настоящее время Африканский континент является одним из наиболее пораженных холерой регионов мира. Ежегодно холерой в Африке заболевают более 55 000 человек. В обзоре проведен сравнительный анализ эпидемических проявлений текущей пандемии, вызванной холерными вибрионами Эль Тор биовара, и шести предыдущих пандемий, вызванных холерными вибрионами классического биовара. Рассмотрены причины масштабного распространения холеры на Африканском континенте в современный период и проблемы ее профилактики.</p></trans-abstract><kwd-group xml:lang="en"><kwd>cholera</kwd><kwd>pandemic</kwd><kwd>epidemic</kwd><kwd>epidemic manifestations</kwd><kwd>cholera vibrios of classical and El Tor biovars</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>холера</kwd><kwd>пандемия</kwd><kwd>эпидемия</kwd><kwd>эпидемические проявления</kwd><kwd>холерные вибрионы классического и Эль Тор биовара</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Буаро М.И., Константинов O.K., Бумбали С., Ришар Ж., Лама Н.Е. Холера в Гвинее: эпидемиология, меры борьбы и профилактики. Инфекционные болезни. 2016, 14 (1): 24-28.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Ганин B.C. По тропам эпидемических катастроф. 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