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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Journal of microbiology, epidemiology and immunobiology</journal-id><journal-title-group><journal-title xml:lang="en">Journal of microbiology, epidemiology and immunobiology</journal-title><trans-title-group xml:lang="ru"><trans-title>Журнал микробиологии, эпидемиологии и иммунобиологии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0372-9311</issn><issn publication-format="electronic">2686-7613</issn><publisher><publisher-name xml:lang="en">Central Research Institute for Epidemiology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">18976</article-id><article-id pub-id-type="doi">10.36233/0372-9311-715</article-id><article-id pub-id-type="edn">YTNXJP</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Next-generation protective gloves: current trends in technological solutions and application prospects (scientific review)</article-title><trans-title-group xml:lang="ru"><trans-title>Защитные перчатки нового поколения: актуальные тенденции технологических решений и перспективы применения (научный обзор)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3416-0902</contrib-id><name-alternatives><name xml:lang="en"><surname>Zakharova</surname><given-names>Yulia A.</given-names></name><name xml:lang="ru"><surname>Захарова</surname><given-names>Юлия Александровна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Dr. Sci. (Med.), Professor, Scientific director, Institute of Disinfection</p></bio><bio xml:lang="ru"><p>д-р мед. наук, профессор, научный руководитель Института дезинфектологии</p></bio><email>zakharova.ya@fncg.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8858-5872</contrib-id><name-alternatives><name xml:lang="en"><surname>Novikov</surname><given-names>Vyacheslav A.</given-names></name><name xml:lang="ru"><surname>Новиков</surname><given-names>Вячеслав Алексеевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>junior researcher, Department of disinfection and sterilization (with microbiology laboratory), Institute of Disinfection</p></bio><bio xml:lang="ru"><p>м. н. с. отдела дезинфекции и стерилизации (с лабораторией микробиологии) Института дезинфектологии</p></bio><email>novikov.va@fncg.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2405-9931</contrib-id><name-alternatives><name xml:lang="en"><surname>Andreev</surname><given-names>Sergey V.</given-names></name><name xml:lang="ru"><surname>Андреев</surname><given-names>Сергей Викторович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Cand. Sci. (Chem.), Deputy Director, Institute of Disinfection, F.F. Erisman Federal Scientific Center of Hygiene</p></bio><bio xml:lang="ru"><p>канд. хим. наук, зам. директора Института дезинфектологии</p></bio><email>svandreev.niid@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3600-2377</contrib-id><name-alternatives><name xml:lang="en"><surname>Makarova</surname><given-names>Mariia A.</given-names></name><name xml:lang="ru"><surname>Макарова</surname><given-names>Мария Александровна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Dr. Sci. (Med.), Associate Professor, senior researcher, Head, Laboratory of enteric infection, Saint-Petersburg Pasteur Institute; Professor, Department of Medical Microbiology, North-Western State Medical University named after I.I. Mechnikov</p></bio><bio xml:lang="ru"><p>д-р мед. наук, доцент, в. н. с., зав. лаб. кишечных инфекций Санкт-Петербургского НИИ эпидемиологии и микробиологии им. Пастера; профессор каф. медицинской микробиологии Северо-Западного государственного медицинского университета им. И.И. Мечникова</p></bio><email>makmaria@mail.ru</email><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff3"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">F.F. Erisman Federal Scientific Center of Hygiene</institution></aff><aff><institution xml:lang="ru">Федеральный научный центр гигиены имени Ф.Ф. Эрисмана</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Saint-Petersburg Pasteur Institute</institution></aff><aff><institution xml:lang="ru">Санкт-Петербургский научно-исследовательский институт эпидемиологии и микробиологии имени Пастера</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">North-Western State Medical University named after I.I. Mechnikov</institution></aff><aff><institution xml:lang="ru">Северо-Западный государственный медицинский университет имени И.И. Мечникова</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2025-11-05" publication-format="electronic"><day>05</day><month>11</month><year>2025</year></pub-date><volume>102</volume><issue>5</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>635</fpage><lpage>646</lpage><history><date date-type="received" iso-8601-date="2025-11-04"><day>04</day><month>11</month><year>2025</year></date><date date-type="accepted" iso-8601-date="2025-11-04"><day>04</day><month>11</month><year>2025</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2025, Zakharova Y.A., Novikov V.A., Andreev S.V., Makarova M.A.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2025, Захарова Ю.А., Новиков В.А., Андреев С.В., Макарова М.А.</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="en">Zakharova Y.A., Novikov V.A., Andreev S.V., Makarova M.A.</copyright-holder><copyright-holder xml:lang="ru">Захарова Ю.А., Новиков В.А., Андреев С.В., Макарова М.А.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://microbiol.crie.ru/jour/article/view/18976">https://microbiol.crie.ru/jour/article/view/18976</self-uri><abstract xml:lang="en"><p><bold>Introduction.</bold> Protective gloves are widely used in medicine to provide biological protection for patients and medical staff. However, if gloves are used improperly, there is a risk of healthcare-associated infections (HAIs) for both staff and patients. A significant problem is the resulting growth in medical waste and its disposal. Therefore, developing new approaches to ensure maximum protection for staff and patients, and minimize the risk of infection, by creating protective gloves based on biodegradable polymer materials with an antimicrobial coating, is an urgent epidemiological and environmental objective.</p> <p>This paper discusses modern technologies and emerging issues in the creation of new materials for protective gloves with antimicrobial properties. These materials can be made using guanidine derivatives, quaternary ammonium compounds (QACs), chlorinated phenols, essential oils, iodine compounds, silver salts, metal oxides and metal nanoparticles and oxides, vegetable oil extracts, aniline dyes. The introduction of biofillers such as starch and nanocellulose will help improve biodegradability. They will also help maintain the necessary physical and chemical characteristics. The problem of synthetic rubber waste disposal can be solved by the development of new composite materials with improved biodegradation characteristics. These materials are in the form of thermoplastic elastomers (TPE), polylactide (PLA) and polylactone (PLC).</p> <p><bold>Conclusion.</bold> A review of the scientific literature revealed a significant global interest in the creation of protective gloves with antimicrobial properties made from biodegradable materials. However, in addition to directly suppressing the growth of pathogenic microflora, their use may also pose a number of problems related to their impact on human health and the ecosystem. The successful implementation of this direction hinges on the continuation of scientific research on imparting the declared properties to gloves. This research should use effective, reliable and safe technologies, as well as the development of unified methods and protocols for assessing antimicrobial activity. Once these are in place, the research can be implemented widely in practice. The production of biodegradable protective gloves offers significant potential, as it will help to reduce the risk of infection spreading in healthcare organizations and contribute to environmental protection.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Введение.</bold> Защитные перчатки широко используют в медицине, они обеспечивают уровень биологической защиты пациентов и медицинского персонала. Вместе с тем существует риск развития инфекций, связанных с оказанием медицинской помощи, у сотрудников и пациентов при их ненадлежащем применении. Значимой проблемой является рост медицинских отходов и их утилизация. В этой связи разработка новых подходов к обеспечению максимальной защиты персонала и пациентов, минимизации риска инфицирования, благодаря созданию защитных перчаток на основе биоразлагаемых полимерных материалов с антимикробным покрытием, является актуальной эпидемиологической и экологической задачей.</p> <p>В статье обсуждаются современные технологии и возникающие проблемы при получении новых материалов для создания защитных перчаток с антимикробными свойствами при использовании производных гуанидина, четвертичных аммониевых соединений, хлорированных фенолов, эфирных масел, соединений йода, солей серебра, частиц и наночастиц металлов и их оксидов, экстрактов растительных масел, анилиновых красителей. Введение таких бионаполнителей, как крахмал и наноцеллюлоза, будет способствовать улучшению биоразлагаемых свойств при сохранении необходимых физико-химических характеристик. Разработка новых композитных материалов с улучшенными характеристиками биодеградации в форме термопластичных эластомеров, полилактида и поликапролактона позволит решить проблему утилизации отходов из синтетического каучука.</p> <p><bold>Заключение. </bold>Анализ современной научной литературы<bold> </bold>определил высокий интерес в мире к созданию защитных перчаток с антимикробными свойствами на основе биоразлагаемых материалов. Однако их применение, кроме непосредственного подавления роста патогенной микрофлоры, может дополнительно нести ряд проблем, связанных с влиянием на здоровье человека и экосистему. Для успешной реализации данного направления важно продолжать научные исследования по приданию перчаткам заявленных свойств с использованием эффективных, надёжных и безопасных технологий с разработкой унифицированных методик и протоколов оценки антимикробной активности для последующего широкого внедрения в практику. Создание биоразлагаемых защитных перчаток имеет большие перспективы, поскольку будет способствовать снижению риска распространения инфекций в медицинских организациях и внесёт существенный вклад в охрану окружающей среды.</p></trans-abstract><kwd-group xml:lang="en"><kwd>protective gloves</kwd><kwd>antimicrobial properties</kwd><kwd>functional materials</kwd><kwd>review</kwd><kwd>biodegradable components</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>защитные перчатки</kwd><kwd>антимикробные свойства</kwd><kwd>функциональные материалы</kwd><kwd>научный обзор</kwd><kwd>биоразлагаемые компоненты</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Konnor R. 2021 national and state healthcare-associated infections progress report;2022. Available at: https://stacks.cdc.gov/view/cdc/122407</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Акимкин В.Г., Брусина Е.Б., Брико Н.И., Тутельян А.В. 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