Journal of microbiology, epidemiology and immunobiologyJournal of microbiology, epidemiology and immunobiologyЖурнал микробиологии, эпидемиологии и иммунобиологии0372-93112686-7613Central Research Institute for Epidemiology14231ArticlesСтатьиROLE OF INFECTIOUS AGENTS IN THE EMERGENCE OF MALIGNANT TUMORSРОЛЬ ИНФЕКЦИОННЫХ АГЕНТОВ В ВОЗНИКНОВЕНИИ ЗЛОКАЧЕСТВЕННЫХ ОПУХОЛЕЙKutikhinA GКутихинА Г

Кемеровская государственная медицинская академия

YuzhalinA EЮжалинА Е

2Кемеровский государственный университет

BrusinaE BБрусинаЕ Б

Кемеровская государственная медицинская академия

BrikoN IБрикоН И

Первыймосковский государственный медицинский университет им. И.М.Сеченова

Кемеровская государственная медицинская академия2Кемеровский государственный университетПервыймосковский государственный медицинский университет им. И.М.Сеченова15102012895NO5 (2012)10411413062023Copyright ©; 2012, Kutikhin A.G., Yuzhalin A.E., Brusina E.B., Briko N.I.Copyright ©; 2012, Кутихин А.Г., Южалин А.Е., Брусина Е.Б., Брико Н.И.2012Kutikhin A.G., Yuzhalin A.E., Brusina E.B., Briko N.I.Кутихин А.Г., Южалин А.Е., Брусина Е.Б., Брико Н.И.https://creativecommons.org/licenses/by/4.0https://microbiol.crie.ru/jour/article/view/14231

According to the data of the International Agency for Research on Cancer (IARC), at least 6 virus species (HPV, EBV, HHV-8/KSHV, HTLV-1, HBV, HCV), 4 helminthes species (Schistosoma haematobium and japonicum, Opisthorchis viverrini, Clonorchis sinensis) and 1 bacterium species (Helicobacter pylori) have been proved to be capable of causing the development of cancer. The analysis of the data available shows that Merkel cell polyomavirus (MCV), herpes simplex virus (HSV), John Cunningham polyomavirus (JCV), monkey virus 40 (SV40), cytomegalovirus (CMV), xenotropic murine leukemia virus (XMRV), Helicobacter bilis and hepaticus, Campylobacter jejuni, Fusobacterium varium, enteropathogenic Escherichia coli, enterotoxigenic Bacteroides fragilis, Bacteroides vulgatus, Prevotella spp., Streptococcus bovis and anginosus, Treponema denticola, Salmonella typhi, paratyphi and typhimurium, Borrelia burgdorferi, Bartonella spp., Mycobacterium tuberculosis, Chlamydia pneumoniae, trachomatis and psittaci, Neisseria gonorrhoeae, Propionibacterium acnes, Tropheryma whippelii, Schistosoma mansoni, Opistorchis felineus, Strongyloides stercoralis, Taenia solium, Candida spp., Paracoccidioides brasiliensis, Histoplasma capsulatum and Trichomonas vaginalis can also be potential etiological agents of cancer. Apparently, detection of new associations between infectious agents and risk of the development of cancer will facilitate progress in elaboration of prophylaxis measures, early diagnostic methods and, probably, methods of treatment of malignant tumors.

Согласно данным Международного агентства по изучению рака (МАИР), как минимум шесть видов вирусов (HPV, EBV, HHV-8/KSHV, HTLV-1, HBV, HCV), четыре вида гельминтов (Schistosoma haematobium и japonicum, Opisthorchis viverrini, Clonorchis sinensis) и один вид бактерий (Helicobacter pylori) достоверно способны приводить к развитию рака. Анализ имеющихся данных показывает, что потенциальными этиологическими агентами рака могут также быть полиомавирус клеток Меркеля (MCV), вирус простого герпеса (HSV), полиомавирус Джона Каннингема (JCV), обезьяний вирус 40 (SV40), цитомегаловирус (CMV), ксенотропный вирус мышиной лейкемии (XMRV), Helicobacter bilis и hepaticus, Campylobacter jejuni, Fusobacterium varium, энтеропатогенная Escherichia coli, энтеротоксигенный Bacteroides fragilis, Bacteroides vulgatus, Prevotella spp., Streptococcus bovis и anginosus, Treponema denticola, Salmonella typhi, paratyphi и typhimurium, Borrelia burgdorferi, Bartonella spp., Mycobacterium tuberculosis, Chlamydia pneumoniae, trachomatis и psittaci, Neisseria gonorrhoeae, Propionibacterium acnes, Tropheryma whippelii, Schistosoma mansoni, Opistorchis felineus, Strongyloides stercoralis, Taenia solium, Candida spp., Paracoccidioides brasiliensis, Histoplasma capsulatum и Trichomonas vaginalis. Очевидно, что выявление новых связей между инфекционными агентами и риском развития рака будет способствовать прогрессу в разработке профилактических мер, методов ранней диагностики и, вероятно, способов лечения злокачественных опухолей.

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