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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Journal of microbiology, epidemiology and immunobiology</journal-id><journal-title-group><journal-title xml:lang="en">Journal of microbiology, epidemiology and immunobiology</journal-title><trans-title-group xml:lang="ru"><trans-title>Журнал микробиологии, эпидемиологии и иммунобиологии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0372-9311</issn><issn publication-format="electronic">2686-7613</issn><publisher><publisher-name xml:lang="en">Central Research Institute for Epidemiology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">13753</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">EPIDEMIOLOGIChESKAYa I EKONOMIChESKAYa EFFEKTIVNOST' ZAKRYTIYa ShKOL PRI EPIDEMIYaKh I PANDEMIYaKh GRIPPA</article-title><trans-title-group xml:lang="ru"><trans-title>ЭПИДЕМИОЛОГИЧЕСКАЯ И ЭКОНОМИЧЕСКАЯ ЭФФЕКТИВНОСТЬ ЗАКРЫТИЯ ШКОЛ ПРИ ЭПИДЕМИЯХ И ПАНДЕМИЯХ ГРИППА</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Gendon</surname><given-names>Yu Z</given-names></name><name xml:lang="ru"><surname>Гендон</surname><given-names>Ю З</given-names></name></name-alternatives><bio xml:lang="ru"><p>НИИ вакцин и сывороток им. И.И. Мечникова. Москва</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Vasil'ev</surname><given-names>Yu M</given-names></name><name xml:lang="ru"><surname>Васильев</surname><given-names>Ю М</given-names></name></name-alternatives><bio xml:lang="ru"><p>НИИ вакцин и сывороток им. И.И. Мечникова. Москва</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">НИИ вакцин и сывороток им. И.И. Мечникова. Москва</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2012-07-15" publication-format="electronic"><day>15</day><month>07</month><year>2012</year></pub-date><volume>89</volume><issue>3</issue><issue-title xml:lang="en">NO3 (2012)</issue-title><issue-title xml:lang="ru">№3 (2012)</issue-title><fpage>113</fpage><lpage>123</lpage><history><date date-type="received" iso-8601-date="2023-06-09"><day>09</day><month>06</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2012, Gendon Y.Z., Vasil'ev Y.M.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2012, Гендон Ю.З., Васильев Ю.М.</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="en">Gendon Y.Z., Vasil'ev Y.M.</copyright-holder><copyright-holder xml:lang="ru">Гендон Ю.З., Васильев Ю.М.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://microbiol.crie.ru/jour/article/view/13753">https://microbiol.crie.ru/jour/article/view/13753</self-uri><abstract xml:lang="en"><p>Epidemiologic and economic effectiveness of school closure during influenza epidemics and
pandemics is discussed. Optimal effect of school closure is observed when this measure is taken at
the start of the epidemic or pandemic and for a sufficiently long time. School closure during high
morbidity among schoolchildren, in the middle (at the peak) and by the end of epidemic or pandemic
does not influence significantly the spread of influenza or morbidity. Significant economic
losses and other negative consequences of school closure are noted. School closure may be the
most appropriate during the emergence of influenza pandemic when the pandemic vaccine is not
yet available, however timely mass immunization of schoolchildren against influenza may be a
more appropriate measure than school closure for the reduction of influenza morbidity and spread
during seasonal influenza epidemics.</p></abstract><trans-abstract xml:lang="ru"><p>В обзоре обсуждаются эпидемиологическая и экономическая эффективность закрытия школ во время эпидемий и пандемий гриппа. Отмечается, что оптимальный эффект закрытия школ наблюдается при реализации этого мероприятия в самом начале эпидемии или пандемии и на достаточно длительное время. Закрытие школ при значительной заболеваемости среди школьников, в середине (на пике) и в конце эпидемии или пандемии существенного влияния на распространение и заболеваемость гриппом не оказывает. Отмечается существенный экономический ущерб, а также другие негативные последствия, связанные с закрытием школ. По мнению авторов, закрытие школ может быть наиболее целесообразно при возникновении пандемии гриппа, учитывая отсутствие пандемической вакцины в начале пандемии, однако для снижения заболеваемости и распространения гриппа при сезонных эпидемиях более рациональным может быть не закрытие школ, а проведение своевременной массовой вакцинации школьников против гриппа.</p></trans-abstract><kwd-group xml:lang="en"><kwd>H1N1 influenza virus</kwd><kwd>epidemic</kwd><kwd>pandemic</kwd><kwd>quarantine measures</kwd><kwd>epidemiologic effectiveness</kwd><kwd>economic effectiveness</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>вирус гриппа H1N1</kwd><kwd>эпидемия</kwd><kwd>пандемия</kwd><kwd>карантинные мероприятия</kwd><kwd>эпидемиологическая эффективность</kwd><kwd>экономическая эффективность</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Гендон Ю.З. 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