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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Journal of microbiology, epidemiology and immunobiology</journal-id><journal-title-group><journal-title xml:lang="en">Journal of microbiology, epidemiology and immunobiology</journal-title><trans-title-group xml:lang="ru"><trans-title>Журнал микробиологии, эпидемиологии и иммунобиологии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0372-9311</issn><issn publication-format="electronic">2686-7613</issn><publisher><publisher-name xml:lang="en">Central Research Institute for Epidemiology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">13725</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">HANTAPULMONARY SYNDROME</article-title><trans-title-group xml:lang="ru"><trans-title>ХАНТАПУЛЬМОНАЛЬНЫЙ СИНДРОМ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Markin</surname><given-names>V A</given-names></name><name xml:lang="ru"><surname>Маркин</surname><given-names>В А</given-names></name></name-alternatives><bio xml:lang="ru"><p>Филиал 48 Центрального НИИ МО РФ -Вирусологический Центр, Сергиев Посад</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Pantyukhov</surname><given-names>V B</given-names></name><name xml:lang="ru"><surname>Пантюхов</surname><given-names>В Б</given-names></name></name-alternatives><bio xml:lang="ru"><p>Филиал 48 Центрального НИИ МО РФ -Вирусологический Центр, Сергиев Посад</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Markov</surname><given-names>V I</given-names></name><name xml:lang="ru"><surname>Марков</surname><given-names>В И</given-names></name></name-alternatives><bio xml:lang="ru"><p>Филиал 48 Центрального НИИ МО РФ -Вирусологический Центр, Сергиев Посад</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Bondarev</surname><given-names>V P</given-names></name><name xml:lang="ru"><surname>Бондарев</surname><given-names>В П</given-names></name></name-alternatives><bio xml:lang="ru"><p>Филиал 48 Центрального НИИ МО РФ -Вирусологический Центр, Сергиев Посад</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Markin</surname><given-names>V A</given-names></name><bio xml:lang="en"><p>Branch of 48th Central Research Institute of Ministryof Defense of Russian Federation - Virology Center,Sergiev Posad, Russia</p></bio><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name><surname>Pantyukhov</surname><given-names>V B</given-names></name><bio xml:lang="en"><p>Branch of 48th Central Research Institute of Ministryof Defense of Russian Federation - Virology Center,Sergiev Posad, Russia</p></bio><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name><surname>Markov</surname><given-names>V I</given-names></name><bio xml:lang="en"><p>Branch of 48th Central Research Institute of Ministryof Defense of Russian Federation - Virology Center,Sergiev Posad, Russia</p></bio><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name><surname>Bondarev</surname><given-names>V P</given-names></name><bio xml:lang="en"><p>Branch of 48th Central Research Institute of Ministryof Defense of Russian Federation - Virology Center,Sergiev Posad, Russia</p></bio><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">Филиал 48 Центрального НИИ МО РФ -Вирусологический Центр, Сергиев Посад</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Branch of 48th Central Research Institute of Ministryof Defense of Russian Federation - Virology Center,Sergiev Posad, Russia</institution></aff><aff><institution xml:lang="ru"></institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2012-03-15" publication-format="electronic"><day>15</day><month>03</month><year>2012</year></pub-date><volume>89</volume><issue>1</issue><issue-title xml:lang="en">NO1 (2012)</issue-title><issue-title xml:lang="ru">№1 (2012)</issue-title><fpage>101</fpage><lpage>107</lpage><history><date date-type="received" iso-8601-date="2023-06-09"><day>09</day><month>06</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2012, Markin V.A., Pantyukhov V.B., Markov V.I., Bondarev V.P., Markin V.A., Pantyukhov V.B., Markov V.I., Bondarev V.P.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2012, Маркин В.А., Пантюхов В.Б., Марков В.И., Бондарев В.П., Markin V.A., Pantyukhov V.B., Markov V.I., Bondarev V.P.</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="en">Markin V.A., Pantyukhov V.B., Markov V.I., Bondarev V.P., Markin V.A., Pantyukhov V.B., Markov V.I., Bondarev V.P.</copyright-holder><copyright-holder xml:lang="ru">Маркин В.А., Пантюхов В.Б., Марков В.И., Бондарев В.П., Markin V.A., Pantyukhov V.B., Markov V.I., Bondarev V.P.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://microbiol.crie.ru/jour/article/view/13725">https://microbiol.crie.ru/jour/article/view/13725</self-uri><abstract xml:lang="en"><p>Features of hantavirus pulmonary syndrome
are considered in the review - zoonosis natural
focal polyetiological viral infection, that is characterized
by lung injury. Etiology of the disease,
main characteristics of the agents, epidemiology,
contagiousness, pathogenesis, clinical presenta -
tion of this pathology are examined. Laboratory
diagnostics, therapy and prophylaxis of hantavirus
pulmonary syndrome are described.</p></abstract><trans-abstract xml:lang="ru"><p>В обзоре рассматриваются особенности
хантавирусного пульмонального синдрома
- зоонозной природно-очаговой полиэтиологической вирусной инфекции, характеризующейся поражением легких. Рассмотрены
этиология заболевания, основные характеристики возбудителей, эпидемиология, контагиозность, патогенез, клиническая картина
этой патологии. Описана лабораторная диагностика, лечение и профилактика хантавирусного пульмонального синдрома.</p></trans-abstract><kwd-group xml:lang="en"><kwd>hantavirus pulmonary syndrome</kwd><kwd>causative agents</kwd><kwd>biological properties</kwd><kwd>spread</kwd><kwd>morbidity</kwd><kwd>clinical presentation</kwd><kwd>diagnostics</kwd><kwd>therapy</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>хантавирусный пульмональный синдром</kwd><kwd>возбудители</kwd><kwd>биологические свойства</kwd><kwd>распространение</kwd><kwd>заболеваемость</kwd><kwd>клиническая картина</kwd><kwd>диагностика</kwd><kwd>лечение</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Жданов В.М. Эволюция вирусов.М., 1990.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Маркин В.А., Марков В.И. Вирусные геморрагические лихорадки - эволюция эпидемического потенциала. Журн. микробиол. 2002, 1: 91-98.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Маркин В.А. Коллекции патогенных вирусов в решении общебиологических проблем. Журн. микробиол. 2007, 6: 84-93.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Мимс С. Значение персистирующих инфекций в природе. Бюллетень ВОЗ. 1976, 4-6, Ч. II: 723-728.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Цилинский Я.Я. Популяционная структура и эволюция вирусов. М., 1988.</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Suzuki A, Bisordi I., Levis S. et al. Identifying rodent hantavirus reservoirs, Brazil. Emerg. Infect. Dis. 2004, 12: 2127-2134.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Bayard V., Kitsutani P.T., Barria E.O. et al. Outbreak of hantavirus pulmonary syndrome, Los Santos, Panama, 1999-2000. Emerg. Infect. Dis. 2004, 9: 1635-1642.</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Bharadwaj M., Mirowsky K., Ye Chunyan et al. Genetic vaccines protect against Sin Nombre hantavirus challenge in the deer mouse (Peromyscus maniculatus). J. Gen. Virol. 2002, 7: 1745-1751.</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Chunyan Ye, Prescjtt J., Nofchissey R. et al. Neutralizing antibodies and Sin Nombre virus RNA after recovery from hantavirus cardiopulmonary syndrome. Emerg. Infect. Dis. 2004, 3: 478-485.</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Cosentini R., Blasi F. New pathogens for respiratory infections. Curr. Opin. Pulm. Med. 1996, 3: 174-180.</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Crowley M.R., Katz R.W., Kessler R. et al. Successful treatment of adults with severe hantavirus pulmonary syndrome with extracorporeal membrane oxygenation. Crit. Care. Med. 1998, 2: 409-414.</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Custer D.M., Thompson E., Schmaljohn C. et al. Active and passive vaccination against hantavirus pulmonary syndrome with Andes virus M genome segment-based DNA vaccine. J. Virol. 2003, 18: 9894-9505.</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>Duchin J.S., Koster F.T., Peters C.J. et al. Hantavirus pulmonary syndrome: A clinical description of 17 patients with a newly recognized disease. The hantavirus study group. N. Engl. J. Med. 1994, 14: 949-955.</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>Enria D., Padula P., Segura E.L. et al. Hantavirus pulmonary syndrome in Argentina. Possibility of person to person transmission. Med. Buenos Aires. 1996, 6: 709-711.</mixed-citation></ref><ref id="B15"><label>15.</label><mixed-citation>Feldmann H., Sanchez A., Morzunov S. et al. Utilization of autopsy RNA for the synthesis of the nucleocapsid antigen of a newly recognized virus associated with hantavirus pulmonary syndrome. Virus. Res. 1993, 3: 351-367.</mixed-citation></ref><ref id="B16"><label>16.</label><mixed-citation>Feuer R., Boone J.D., Netski Dale et al. Temporal and spatial analysis of Sin Nombre virus quasispecies in naturally infected rodents. J. Virol. 1999, 11: 9544-9554.</mixed-citation></ref><ref id="B17"><label>17.</label><mixed-citation>Frey M.T., Vial P.C., Castillo C.H. et al. Hantavirus prevalence in the IX region of Chile. Emerg. Infect. Dis. 2003, 7: 827-832.</mixed-citation></ref><ref id="B18"><label>18.</label><mixed-citation>Gavrilovskaya I., Brown E.J., Ginsberg M.H et al. Cellular entry of hantaviruses which cause haemorrhagic fever with renal syndrome is mediated by b [3] integrins. J. Virol. 1999, 5: 3951-3959.</mixed-citation></ref><ref id="B19"><label>19.</label><mixed-citation>Harrisons principles of internal medicine. E. Braunwald et al. (ed). McGraw-Hill Comp., 1998.</mixed-citation></ref><ref id="B20"><label>20.</label><mixed-citation>Hejele B., Jenison S., Torrez-Martinez N. et al. A novel hantavirus associated with an outbreak of fatal respiratory disease in the southwestern United States: Evolutionary relationships to known hantaviruses. J. Virol. 1994, 2: 592-596.</mixed-citation></ref><ref id="B21"><label>21.</label><mixed-citation>Hooper J.W., Larsen T., Custer D.M. A lethal disease model for hantavirus pulmonary syndrome. Virology. 2001, 289: 6-14.</mixed-citation></ref><ref id="B22"><label>22.</label><mixed-citation>Hooper J.W., Ferro A.M., Wahl-Jensen V. Immune serum by DNA vaccination protects hamsters against lethal respiratory challenge with Andes virus. J. Virol. 2008, 3: 1332-1338.</mixed-citation></ref><ref id="B23"><label>23.</label><mixed-citation>Hopkins R.O., Larson L.V., Weaver L.K et al. Neuropsychological impairments following hantavirus pulmonary syndrome. J. Int. Neuropsychol. Soc. 1998, 2: 190-196.</mixed-citation></ref><ref id="B24"><label>24.</label><mixed-citation>Jenison S., Yamada T., Morris C. et al. Characterization of human antibody responses to Four Corners hantavirus infections among patients with hantavirus pulmonary syndrome. J. Virol. 1994, 1: 3000-3006.</mixed-citation></ref><ref id="B25"><label>25.</label><mixed-citation>McCaughey C., Hart C.A. Hantaviruses. J. Med. Microbiol. 2000, 49: 587-599.</mixed-citation></ref><ref id="B26"><label>26.</label><mixed-citation>Mcintyre N.E., Young-Kyu Chu, Owen R.D. et al. A longitudinal study of Bayou virus, hosts, and habitat. Am. J. Trop. Med. Hyg. 2005, 6: 1043-1049.</mixed-citation></ref><ref id="B27"><label>27.</label><mixed-citation>Mertz S.J., Miedzinski L., Goade D. et al. Placebo-controlled, double-blind trial of intravenous ribavirin for the treatment of hantavirus cardiopulmonary syndrome in North America. Clin. Infect. Dis. 2004, 39: 1307-1313.</mixed-citation></ref><ref id="B28"><label>28.</label><mixed-citation>Mills J.N., Ksiazek T.G., Peters C.J. et al. Longterm studies of hantavirus populations in the southwestern United States: A synthesis. Emerg. Infect. Dis. 1999, 1: 135-142.</mixed-citation></ref><ref id="B29"><label>29.</label><mixed-citation>Monroe M.C., Morzunov S.P., Johnson A.M. et al. Genetic diversity and distribution of Peromyscus-borne hantaviruses in North America. Emerg. Infect. Dis. 1999, 1: 75-86.</mixed-citation></ref><ref id="B30"><label>30.</label><mixed-citation>Morzunov S.P., Rowe J.E., Ksiazek T.G. Genetic analysis of the diversity and origin of hantaviruses in Peromyscus leucopus mice in North America. J. Virol. 1998, 1: 57-64.</mixed-citation></ref><ref id="B31"><label>31.</label><mixed-citation>Murgue B., Domart Y., Coudrier D. et al. First reported case of imported hantavirus pulmonary syndrome in Europe. Emerg. Infect. Dis. 2002, 1: 106-107.</mixed-citation></ref><ref id="B32"><label>32.</label><mixed-citation>Netski D., Thran B.H., Jeor S.C. Sin Nombre virus pathogenesis in Peromyscus maniculatus. J. Virol. 1999, 1: 585-591.</mixed-citation></ref><ref id="B33"><label>33.</label><mixed-citation>Nichol S., Spiropoulou C., Morzunov S. et al. Genetic identification of a hantavirus associated with an outbreak of acute respiratory illness. Science. 1993, 262: 914-917.</mixed-citation></ref><ref id="B34"><label>34.</label><mixed-citation>Passaro D.J., Shieh Wun-Ju,Hacker J. et al. Predominant kidney involvement in a fatal case of hantavirus pulmonary syndrome caused by Sin Nombre virus. Clin. Infect. Dis. 2001, 2: 263-264.</mixed-citation></ref><ref id="B35"><label>35.</label><mixed-citation>Schmaljohn C., Hjelle B. Hantaviruses: A global disease problem. Em. Infect. Dis. 1997, 2: 95-104.</mixed-citation></ref><ref id="B36"><label>36.</label><mixed-citation>Shope R.E. A midcourse assessment of hantavirus pulmonary syndrome. Emerg. Infect. Dis. 1999, 1: 172-174.</mixed-citation></ref><ref id="B37"><label>37.</label><mixed-citation>Verity R., Prasad E., Grimsrud K. et al. Hantavirus pulmonary syndrome in northern Alberta, Canada. Clinical and laboratory findings for 19 cases. Clin. Infect. Dis. 2000, 4: 942-946.</mixed-citation></ref><ref id="B38"><label>38.</label><mixed-citation>Virus taxonomy: The classification and nomenclature of viruses. M.H.V. van Regenmortel, C.M. Fauquet, D.H.L. Bishop et al. (ed.). San Diego, 2000.</mixed-citation></ref><ref id="B39"><label>39.</label><mixed-citation>Vitek C.R., Breiman R.F., Ksiazek T.G. et al. Evidence against person to person transmission of hantavirus to health care workers. Clin. Infect. Dis. 1996, 5: 824-826.</mixed-citation></ref><ref id="B40"><label>40.</label><mixed-citation>Wells R.M., Young J., Williams R.J. et al. Hantavirus transmission in the United States. Emerg. Infect. Dis. 1997, 3: 361-365.</mixed-citation></ref></ref-list></back></article>
