Journal of microbiology, epidemiology and immunobiologyJournal of microbiology, epidemiology and immunobiologyЖурнал микробиологии, эпидемиологии и иммунобиологии0372-93112686-7613Central Research Institute for Epidemiology13360ArticlesСтатьиReview ArticleANTIBACTERIAL AND ANTIMYCOTIC ACTIVITY OF CHITOSAN: MECHANISMS OF ACTION AND ROLE OF THE STRUCTUREАНТИБАКТЕРИАЛЬНАЯ И АНТИМИКОТИЧЕСКАЯ АКТИВНОСТЬ ХИТОЗАНА: МЕХАНИЗМЫ ДЕЙСТВИЯ И РОЛЬ СТРУКТУРЫKulikovS. NКуликовС. НTyurinYu. AТюринЮ. АFassakhovR. SФассаховР. СVarlamovV. PВарламовВ. ПResearch Institute of Epidemiology and Microbiology, KazanКазанский НИИ эпидемиологии и микробиологииCenter «Bioengineering», Moscow, RussiaЦентр «Биоинженерия» РАН, Москва15102009865NO5 (2009)№5 (2009)919709062023Copyright ©; 2009, Kulikov S.N., Tyurin Y.A., Fassakhov R.S., Varlamov V.P.Copyright ©; 2009, Куликов С.Н., Тюрин Ю.А., Фассахов Р.С., Варламов В.П.2009Kulikov S.N., Tyurin Y.A., Fassakhov R.S., Varlamov V.P.Куликов С.Н., Тюрин Ю.А., Фассахов Р.С., Варламов В.П.https://creativecommons.org/licenses/by/4.0https://microbiol.crie.ru/jour/article/view/13360

Chitosan biopolymer obtained by deacetylation of chitin has antibacterial and antimycotic action. Known data about mechanisms of biocide effect of chitosan are described in the review. Role of chemical structure — molecular weight, level of deacetylation and presence of nanoparticles — in the expression of antibacterial and antimycotic activity is discussed.

Хитозановый биополимер, получаемый методом деацетилирования из хитина, обладает антибактериальным и антимикотическим действием. В обзоре приводятся известные на сегодняшний день данные о механизмах биоцидного действия хитозана. Обсуждается роль химической структуры хитозанового полимера — молекулярной массы, степени деацетилирования и наночастиц в проявлении им антибактериальной и антимикотической активности.

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